Linked Life Data

12899738

Source:http://linkedlifedata.com/resource/pubmed/id/12899738

Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
1
pubmed:dateCreated
2003-8-5
pubmed:abstractText
Early in the last century, neuroscientists initially speculated that it might be possible to influence brain activity and associated behaviours by stimulating the vagus nerve in the neck. Several animal studies pointed to this possibility. In the 1980s, Zabara discovered that vagus nerve stimulation (VNS) could reduce or eliminate seizures in dogs. His discovery led to enhanced methods of direct VNS and the development of an implantable device for human VNS. VNS is now an accepted long-term treatment for epilepsy, used by over 15000 patients worldwide. Many have wondered whether VNS could treat other neuropsychiatric disorders. This paper reviews the neurobiology involved in VNS, highlights the VNS clinical findings to date, and discusses potential VNS research opportunities for both clinical and basic investigators. Comments on the clinical utility of VNS in actual clinical practice are provided.
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:status
MEDLINE
pubmed:month
Mar
pubmed:issn
1469-5111
pubmed:author
pubmed:issnType
Electronic
pubmed:volume
6
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
73-83
pubmed:meshHeading
pubmed:year
2003
pubmed:articleTitle
Vagus nerve stimulation (VNS): utility in neuropsychiatric disorders.
pubmed:affiliation
Brain Stimulation Laboratory, Department of Psychiatry, Center for Advanced Imaging Research, Medical University of South Carolina, Charleston, SC 29425, USA. georgem@musc.edu
pubmed:publicationType
Journal Article, Review, Historical Article