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rdf:type |
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lifeskim:mentions |
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pubmed:issue |
2
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pubmed:dateCreated |
2003-7-31
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pubmed:abstractText |
Adefovir dipivoxil effectively inhibits both hepatitis B virus (HBV) replication and disease activity in patients with chronic hepatitis B. Resistance to treatment was not observed in 2 recent large placebo-controlled 48-week studies with this drug. The aim of this study was to characterize adefovir resistance in a patient who developed clinical and virologic evidence of breakthrough during a 96-week course of treatment.
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pubmed:language |
eng
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pubmed:journal |
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pubmed:citationSubset |
AIM
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pubmed:chemical |
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pubmed:status |
MEDLINE
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pubmed:month |
Aug
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pubmed:issn |
0016-5085
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pubmed:author |
pubmed-author:AngusPeterP,
pubmed-author:BartholomeuszAngelineA,
pubmed-author:BisolAA,
pubmed-author:BrosgartCarolC,
pubmed-author:ColledgeDanielleD,
pubmed-author:DelaneyWilliamW,
pubmed-author:EdwardsRosalindR,
pubmed-author:GibbsCraigC,
pubmed-author:LocarniniStephenS,
pubmed-author:VaughanRhysR,
pubmed-author:XiongShellyS,
pubmed-author:YangHuilingH
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pubmed:issnType |
Print
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pubmed:volume |
125
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
292-7
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pubmed:dateRevised |
2004-11-17
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pubmed:meshHeading |
pubmed-meshheading:12891527-Adenine,
pubmed-meshheading:12891527-Alanine Transaminase,
pubmed-meshheading:12891527-Antiviral Agents,
pubmed-meshheading:12891527-DNA, Viral,
pubmed-meshheading:12891527-DNA-Directed DNA Polymerase,
pubmed-meshheading:12891527-Drug Resistance, Viral,
pubmed-meshheading:12891527-Hepatitis B, Chronic,
pubmed-meshheading:12891527-Hepatitis B virus,
pubmed-meshheading:12891527-Humans,
pubmed-meshheading:12891527-Male,
pubmed-meshheading:12891527-Middle Aged,
pubmed-meshheading:12891527-Mutation,
pubmed-meshheading:12891527-Phosphonic Acids,
pubmed-meshheading:12891527-Viral Proteins
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pubmed:year |
2003
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pubmed:articleTitle |
Resistance to adefovir dipivoxil therapy associated with the selection of a novel mutation in the HBV polymerase.
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pubmed:affiliation |
Austin Hospital, Studley Road, Heidelberg, Victoria 3084, Australia. peter.angus@armc.org.au
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pubmed:publicationType |
Journal Article
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