12890205

Source:http://linkedlifedata.com/resource/pubmed/id/12890205

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Predicate	Object
rdf:type	pubmed:Citation
lifeskim:mentions	umls-concept:C0002563, umls-concept:C0022086, umls-concept:C0031740, umls-concept:C0072497, umls-concept:C0332237, umls-concept:C0441889, umls-concept:C1280500, umls-concept:C1522168, umls-concept:C1527358
pubmed:issue	1
pubmed:dateCreated	2003-7-31
pubmed:abstractText	In 5-aminolaevulinic acid (ALA)-photodynamic therapy (PDT), the prodrug ALA is endogenously converted to the active sensitizer protoporphyrin IX (PpIX), while further conversion of PpIX to haem requires iron.
pubmed:language	eng
pubmed:journal	http://linkedlifedata.com/resource/pubmed/journal/0004041
pubmed:citationSubset	IM
pubmed:chemical	http://linkedlifedata.com/resource/pubmed/chemical/Aminolevulinic Acid, http://linkedlifedata.com/resource/pubmed/chemical/Deferoxamine, http://linkedlifedata.com/resource/pubmed/chemical/Iron Chelating Agents, http://linkedlifedata.com/resource/pubmed/chemical/Protoporphyrins, http://linkedlifedata.com/resource/pubmed/chemical/protoporphyrin IX
pubmed:status	MEDLINE
pubmed:month	Jul
pubmed:issn	0007-0963
pubmed:author	pubmed-author:BrookeR C CRC, pubmed-author:ChoudryKK, pubmed-author:FarrarWW, pubmed-author:RhodesL ELE
pubmed:issnType	Print
pubmed:volume	149
pubmed:owner	NLM
pubmed:authorsComplete	Y
pubmed:pagination	124-30
pubmed:dateRevised	2006-11-15
pubmed:meshHeading	pubmed-meshheading:12890205-Administration, Cutaneous, pubmed-meshheading:12890205-Adult, pubmed-meshheading:12890205-Aged, pubmed-meshheading:12890205-Aged, 80 and over, pubmed-meshheading:12890205-Aminolevulinic Acid, pubmed-meshheading:12890205-Bowen's Disease, pubmed-meshheading:12890205-Carcinoma, Basal Cell, pubmed-meshheading:12890205-Deferoxamine, pubmed-meshheading:12890205-Dose-Response Relationship, Drug, pubmed-meshheading:12890205-Drug Therapy, Combination, pubmed-meshheading:12890205-Erythema, pubmed-meshheading:12890205-Female, pubmed-meshheading:12890205-Fluorescence, pubmed-meshheading:12890205-Humans, pubmed-meshheading:12890205-Iontophoresis, pubmed-meshheading:12890205-Iron Chelating Agents, pubmed-meshheading:12890205-Male, pubmed-meshheading:12890205-Middle Aged, pubmed-meshheading:12890205-Photochemotherapy, pubmed-meshheading:12890205-Protoporphyrins, pubmed-meshheading:12890205-Skin Neoplasms
pubmed:year	2003
pubmed:articleTitle	The effect of an iron chelating agent on protoporphyrin IX levels and phototoxicity in topical 5-aminolaevulinic acid photodynamic therapy.
pubmed:affiliation	Photobiology Unit, Dermatology Centre, Hope Hospital, Salford, Manchester M6 8HD, U.K.
pubmed:publicationType	Journal Article, Clinical Trial, Research Support, Non-U.S. Gov't