rdf:type |
|
lifeskim:mentions |
umls-concept:C0001430,
umls-concept:C0017262,
umls-concept:C0185117,
umls-concept:C0249197,
umls-concept:C0288472,
umls-concept:C0333983,
umls-concept:C0441655,
umls-concept:C0443324,
umls-concept:C1266025,
umls-concept:C1332737,
umls-concept:C1420626,
umls-concept:C1516044,
umls-concept:C1548559,
umls-concept:C1707455,
umls-concept:C2911684
|
pubmed:issue |
8
|
pubmed:dateCreated |
2003-8-15
|
pubmed:abstractText |
Serrated adenomas (SAs), which include a wide spectrum of lesions, can be broadly divided into two subtypes: type I, closely mimicking hyperplastic polyps (HPs), and type II, unequivocal adenomatous tumor. Our preliminary findings showed clinicopathologic differences between them. The present study was conducted to investigate apoptotic activity and expression of the cell cycle regulator proteins p21(WAF1/CIP1) and p27(Kip1) in type I and II SAs, as compared with traditional adenomas (TAs) and HPs.
|
pubmed:language |
eng
|
pubmed:journal |
|
pubmed:citationSubset |
IM
|
pubmed:chemical |
|
pubmed:status |
MEDLINE
|
pubmed:month |
Aug
|
pubmed:issn |
0171-5216
|
pubmed:author |
|
pubmed:issnType |
Print
|
pubmed:volume |
129
|
pubmed:owner |
NLM
|
pubmed:authorsComplete |
Y
|
pubmed:pagination |
449-55
|
pubmed:dateRevised |
2006-11-15
|
pubmed:meshHeading |
pubmed-meshheading:12884030-Adenoma,
pubmed-meshheading:12884030-Adult,
pubmed-meshheading:12884030-Aged,
pubmed-meshheading:12884030-Aged, 80 and over,
pubmed-meshheading:12884030-Apoptosis,
pubmed-meshheading:12884030-Cell Cycle Proteins,
pubmed-meshheading:12884030-Colonic Polyps,
pubmed-meshheading:12884030-Cyclin-Dependent Kinase Inhibitor p21,
pubmed-meshheading:12884030-Cyclin-Dependent Kinase Inhibitor p27,
pubmed-meshheading:12884030-Cyclins,
pubmed-meshheading:12884030-Enzyme Inhibitors,
pubmed-meshheading:12884030-Female,
pubmed-meshheading:12884030-Gene Expression Regulation, Neoplastic,
pubmed-meshheading:12884030-Humans,
pubmed-meshheading:12884030-Hyperplasia,
pubmed-meshheading:12884030-Immunohistochemistry,
pubmed-meshheading:12884030-Male,
pubmed-meshheading:12884030-Middle Aged,
pubmed-meshheading:12884030-Tumor Suppressor Proteins
|
pubmed:year |
2003
|
pubmed:articleTitle |
Different apoptotic activity and p21(WAF1/CIP1), but not p27(Kip1), expression in serrated adenomas as compared with traditional adenomas and hyperplastic polyps of the colorectum.
|
pubmed:affiliation |
Department of Pathology, National Sagamihara Hospital, 18-1 Sakura-dai, 228-8522, Sagamihara, Kanagawa, Japan. h-mitomi@sagamihara-hosp.gr.jp
|
pubmed:publicationType |
Journal Article,
Comparative Study,
Research Support, Non-U.S. Gov't
|