Linked Life Data

12883682

Source:http://linkedlifedata.com/resource/pubmed/id/12883682

Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
5
pubmed:dateCreated
2003-7-28
pubmed:abstractText
Thymidine phosphorylase (dThdPase) is known to promote the development of new blood vessels. Increased dThdPase expression in solid tumors has been shown to correlate with tumor growth, invasion and metastasis. In the present study, we measured dThdPase levels in the tumor tissue and in the serum from the tumor drainage and peripheral venous blood obtained from patients with resectable colorectal cancer. Serum dThdPase levels, measured by a modified ELISA method, were significantly higher in patients with hematogenous metastasis. In the tumor tissue specimens, no significant difference was observed between patients with or without hematogenous metastasis. These results suggest that the serum dThdPase levels are a novel marker to predict occurrence of hematogenous metastasis in patients with resectable colorectal cancer.
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:chemical
pubmed:status
MEDLINE
pubmed:issn
1021-335X
pubmed:author
pubmed:issnType
Print
pubmed:volume
10
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
1207-12
pubmed:dateRevised
2004-11-17
pubmed:meshHeading
pubmed:articleTitle
Occurrence of hematogenous metastasis and serum levels of thymidine phosphorylase in colorectal cancer.
pubmed:affiliation
Department of Surgery, Graduate School of Biochemical Sciences, Nagasaki University, Nagasaki 852-8501, Japan. haraguci@mb.ejnet.ne.jp
pubmed:publicationType
Journal Article