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rdf:type |
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lifeskim:mentions |
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pubmed:issue |
8
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pubmed:dateCreated |
2003-7-28
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pubmed:abstractText |
Macrophage recruitment to the choroid has been proposed to contribute to the pathogenesis of choroidal neovascularization (CNV) in AMD. The study was conducted to determine whether treatment with clodronate liposomes (CL(2)MDP-lip), which cause depletion of blood monocytes and lymph node macrophages, diminishes the severity of neovascularization in a mouse model of laser-induced CNV.
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pubmed:grant |
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pubmed:language |
eng
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pubmed:journal |
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pubmed:citationSubset |
IM
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pubmed:chemical |
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pubmed:status |
MEDLINE
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pubmed:month |
Aug
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pubmed:issn |
0146-0404
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pubmed:author |
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pubmed:issnType |
Print
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pubmed:volume |
44
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
3586-92
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pubmed:dateRevised |
2007-11-14
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pubmed:meshHeading |
pubmed-meshheading:12882811-Animals,
pubmed-meshheading:12882811-Antimetabolites,
pubmed-meshheading:12882811-Cell Count,
pubmed-meshheading:12882811-Choroid,
pubmed-meshheading:12882811-Choroidal Neovascularization,
pubmed-meshheading:12882811-Clodronic Acid,
pubmed-meshheading:12882811-Dextrans,
pubmed-meshheading:12882811-Disease Models, Animal,
pubmed-meshheading:12882811-Female,
pubmed-meshheading:12882811-Flow Cytometry,
pubmed-meshheading:12882811-Fluoresceins,
pubmed-meshheading:12882811-Liposomes,
pubmed-meshheading:12882811-Macrophages,
pubmed-meshheading:12882811-Mice,
pubmed-meshheading:12882811-Mice, Inbred C57BL
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pubmed:year |
2003
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pubmed:articleTitle |
Macrophage depletion diminishes lesion size and severity in experimental choroidal neovascularization.
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pubmed:affiliation |
Bascom Palmer Eye Institute, Department of Ophthalmology, The University of Miami School of Medicine, Miami, Florida, USA.
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pubmed:publicationType |
Journal Article,
Research Support, U.S. Gov't, P.H.S.
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