Linked Life Data

12877890

Source:http://linkedlifedata.com/resource/pubmed/id/12877890

Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
1
pubmed:dateCreated
2003-7-24
pubmed:abstractText
We retrospectively analyzed data on 628 leukapheresis from 160 consecutive patients with hematologic or solid malignancies to identify predictive factors affecting the achievement of optimal peripheral blood progenitor cell (PBPC) collection, which was defined as > or = 5x10(6) CD34+ cells/kg. In univariate analysis, a diagnosis of multiple myeloma, no prior axial skeletal radiotherapy, absence of exposure to alkylating agents and cisplatin, fewer cycles of chemotherapy, and fewer number of previous chemotherapy regimens favored the achievement of target number of PBPC. In multivariate analysis, the absence of prior exposure to alkylating agents, especially cyclophosphamide, (P=0.003, RR=2.08) and cisplatin (P=0.015, RR=2.50) were independent predicting factors affecting the probability of achieving the target PBPC and the time to reach the target PBPC collection. In addition, the total dose of cyclophosphamide the patient received significantly alters the mobilization.
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
T
pubmed:chemical
pubmed:status
MEDLINE
pubmed:month
Aug
pubmed:issn
1473-0502
pubmed:author
pubmed:issnType
Print
pubmed:volume
29
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
29-37
pubmed:dateRevised
2007-11-15
pubmed:meshHeading
pubmed:year
2003
pubmed:articleTitle
Collection of peripheral blood progenitor cells: analysis of factors predicting the yields.
pubmed:affiliation
Department of Medicine, University of Ulsan College of Medicine, Asan Medical Center, 388-1 Poongnap-dong, Songpa-gu, Seoul 138-040, South Korea. jaelyun@amc.seoul.kr
pubmed:publicationType
Journal Article