Source:http://linkedlifedata.com/resource/pubmed/id/12877454
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| Predicate | Object |
|---|---|
| rdf:type | |
| lifeskim:mentions | |
| pubmed:issue |
1
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| pubmed:dateCreated |
2003-7-24
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| pubmed:abstractText |
The nature of histamine-releasing factors involved in the pathogenesis of chronic idiopathic urticaria (CIU) is still controversial, since functional IgG autoantibodies specific for the high-affinity IgE receptor, Fc(epsilon)RI, can be detected in only 20% of patients showing a strong skin reactivity on the autologous serum skin test. The absence of systemic eosinophilia in CIU patients, along with the increase in mast cells in skin biopsy specimens, suggests a possible role for stem cell factor (SCF), the only cytokine/growth factor known to induce mediator release from human mast cells.
|
| pubmed:language |
eng
|
| pubmed:journal | |
| pubmed:citationSubset |
IM
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| pubmed:chemical | |
| pubmed:status |
MEDLINE
|
| pubmed:month |
Jul
|
| pubmed:issn |
1081-1206
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| pubmed:author | |
| pubmed:issnType |
Print
|
| pubmed:volume |
91
|
| pubmed:owner |
NLM
|
| pubmed:authorsComplete |
Y
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| pubmed:pagination |
79-81
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| pubmed:dateRevised |
2004-11-17
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| pubmed:meshHeading |
pubmed-meshheading:12877454-Autoantibodies,
pubmed-meshheading:12877454-Eosinophilia,
pubmed-meshheading:12877454-Histamine Release,
pubmed-meshheading:12877454-Humans,
pubmed-meshheading:12877454-Mast Cells,
pubmed-meshheading:12877454-Receptors, IgE,
pubmed-meshheading:12877454-Skin Tests,
pubmed-meshheading:12877454-Stem Cell Factor,
pubmed-meshheading:12877454-Urticaria
|
| pubmed:year |
2003
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| pubmed:articleTitle |
Circulating stem cell factor in patients with chronic idiopathic urticaria.
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| pubmed:affiliation |
Ambulatorio di Allergologia, Clinica San Carlo, Paderno Dugnano (MI), Italy. r.asero@libero.it
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| pubmed:publicationType |
Journal Article
|