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rdf:type |
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lifeskim:mentions |
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pubmed:issue |
5
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pubmed:dateCreated |
2003-7-24
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pubmed:abstractText |
There is a heritable component to suicidal behaviour, encouraging the search for the associated risk alleles. Given the putative role of the 5-HT (5-hydroxytryptamine; serotonin) system in suicidal behaviour, serotonergic genes are leading candidates. In particular, several studies have reported an association with variants in the tryptophan hydroxylase (TPH) gene.
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pubmed:language |
eng
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pubmed:journal |
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pubmed:citationSubset |
IM
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pubmed:chemical |
http://linkedlifedata.com/resource/pubmed/chemical/Carrier Proteins,
http://linkedlifedata.com/resource/pubmed/chemical/Membrane Glycoproteins,
http://linkedlifedata.com/resource/pubmed/chemical/Membrane Transport Proteins,
http://linkedlifedata.com/resource/pubmed/chemical/Monoamine Oxidase,
http://linkedlifedata.com/resource/pubmed/chemical/Nerve Tissue Proteins,
http://linkedlifedata.com/resource/pubmed/chemical/Receptor, Serotonin, 5-HT2C,
http://linkedlifedata.com/resource/pubmed/chemical/Receptors, Serotonin,
http://linkedlifedata.com/resource/pubmed/chemical/SLC6A4 protein, human,
http://linkedlifedata.com/resource/pubmed/chemical/Serotonin,
http://linkedlifedata.com/resource/pubmed/chemical/Serotonin Plasma Membrane...,
http://linkedlifedata.com/resource/pubmed/chemical/Tryptophan Hydroxylase
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pubmed:status |
MEDLINE
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pubmed:month |
Jul
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pubmed:issn |
0033-2917
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pubmed:author |
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pubmed:issnType |
Print
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pubmed:volume |
33
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
775-83
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pubmed:dateRevised |
2006-11-15
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pubmed:meshHeading |
pubmed-meshheading:12877392-Adult,
pubmed-meshheading:12877392-Aged,
pubmed-meshheading:12877392-Alleles,
pubmed-meshheading:12877392-Carrier Proteins,
pubmed-meshheading:12877392-Case-Control Studies,
pubmed-meshheading:12877392-Female,
pubmed-meshheading:12877392-Humans,
pubmed-meshheading:12877392-Male,
pubmed-meshheading:12877392-Membrane Glycoproteins,
pubmed-meshheading:12877392-Membrane Transport Proteins,
pubmed-meshheading:12877392-Middle Aged,
pubmed-meshheading:12877392-Monoamine Oxidase,
pubmed-meshheading:12877392-Nerve Tissue Proteins,
pubmed-meshheading:12877392-Polymorphism, Genetic,
pubmed-meshheading:12877392-Receptor, Serotonin, 5-HT2C,
pubmed-meshheading:12877392-Receptors, Serotonin,
pubmed-meshheading:12877392-Risk Factors,
pubmed-meshheading:12877392-Self-Injurious Behavior,
pubmed-meshheading:12877392-Serotonin,
pubmed-meshheading:12877392-Serotonin Plasma Membrane Transport Proteins,
pubmed-meshheading:12877392-Suicide,
pubmed-meshheading:12877392-Tryptophan Hydroxylase
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pubmed:year |
2003
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pubmed:articleTitle |
Deliberate self-harm is associated with allelic variation in the tryptophan hydroxylase gene (TPH A779C), but not with polymorphisms in five other serotonergic genes.
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pubmed:affiliation |
University Department of Psychiatry and Centre for Suicide Research, Warneford Hospital, University of Oxford.
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pubmed:publicationType |
Journal Article,
Comparative Study,
Research Support, Non-U.S. Gov't
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