Linked Life Data

12877382

Source:http://linkedlifedata.com/resource/pubmed/id/12877382

Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
4
pubmed:dateCreated
2003-7-24
pubmed:abstractText
New molecular techniques such as cDNA, protein or antibody arrays allow for high-throughput identification of thousands of potentially disease-related markers on the genome, transcriptome and proteome level. Major disadvantages of such studies are the enormous costs and the need for unfixed tissues, disallowing comprehensive large-scale studies. Consequently, validation studies including large sets of clinically well-defined tissue samples are now necessary to identify those genes or proteins with true impact on the course of disease which will eventually lead to therapeutic applications. Tissue microarray technology overcomes the bottleneck of traditional tissue analysis and allows it to catch up with the rapid advances in lead discovery. Current applications and the future potential of tissue microarray technology in cancer research and diagnosis are discussed.
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:status
MEDLINE
pubmed:month
Jul
pubmed:issn
1473-7159
pubmed:author
pubmed:issnType
Print
pubmed:volume
3
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
421-30
pubmed:dateRevised
2005-11-16
pubmed:meshHeading
pubmed:year
2003
pubmed:articleTitle
Tissue microarrays in cancer diagnosis.
pubmed:affiliation
Institute of Pathology, Division of Molecular Pathology, University of Basel, Switzerland. Ronald.Simon@unibas.ch
pubmed:publicationType
Journal Article, Review