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rdf:type |
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lifeskim:mentions |
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pubmed:issue |
3
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pubmed:dateCreated |
2003-7-23
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pubmed:abstractText |
A reduction of IL-12 production by lung macrophages may partly explain the presumed adjuvant effect of diesel exhaust particles (DEP) in allergy and asthma. IL-12 stimulates T helper type 1 (Th1) lymphocytes, which inhibit Th2 cells via Th1-specific cytokines. The aim of this study was to investigate the influence of DEP on the production of IL-12 p40 in lipopolysaccharide (LPS)-activated monocytes.
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pubmed:language |
eng
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pubmed:journal |
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pubmed:citationSubset |
IM
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pubmed:chemical |
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pubmed:status |
MEDLINE
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pubmed:month |
Jul
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pubmed:issn |
1018-2438
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pubmed:author |
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pubmed:copyrightInfo |
Copyright 2003 S. Karger AG, Basel
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pubmed:issnType |
Print
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pubmed:volume |
131
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
201-8
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pubmed:dateRevised |
2006-11-15
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pubmed:meshHeading |
pubmed-meshheading:12876411-Asthma,
pubmed-meshheading:12876411-Cell Line,
pubmed-meshheading:12876411-Down-Regulation,
pubmed-meshheading:12876411-Humans,
pubmed-meshheading:12876411-Hypersensitivity, Immediate,
pubmed-meshheading:12876411-Interleukin-12,
pubmed-meshheading:12876411-Lipopolysaccharides,
pubmed-meshheading:12876411-Monocytes,
pubmed-meshheading:12876411-Particle Size,
pubmed-meshheading:12876411-Protein Subunits,
pubmed-meshheading:12876411-Tumor Necrosis Factor-alpha,
pubmed-meshheading:12876411-Vehicle Emissions
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pubmed:year |
2003
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pubmed:articleTitle |
Reduction of IL-12 p40 production in activated monocytes after exposure to diesel exhaust particles.
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pubmed:affiliation |
Department of Cancer Research and Molecular Medicine, Faculty of Medicine, Norwegian University of Science and Technology, Trondheim, Norway. asbjorn.nilsen@medisin.ntnu.no
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pubmed:publicationType |
Journal Article,
Research Support, Non-U.S. Gov't
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