Linked Life Data

12875350

Source:http://linkedlifedata.com/resource/pubmed/id/12875350

Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
2
pubmed:dateCreated
2003-7-23
pubmed:abstractText
Every diagnostic test causes additional cost if not additional risk. The cost and risk are justified if the test result is likely to change what is done for patients. This includes a diagnostic test that does not alter therapy but provides important prognostic information for the parents. Whether the test result changes therapy depends on: the action threshold (the probability of disease at which the clinician offers the therapy or intervention because it would do more good than harm). the patient's pretest probability of disease. the test performance (measured by LRs, sensitivity, and specificity). For all tests there is an inverse relationship or trade-offbetween sensitivity and specificity. A good diagnostic test is one in which this trade-off is relatively small within the range of sensitivities and specificities that are clinically relevant. When diagnostic tests are used in low-risk subjects (as in screening tests), the performance of the test is critical because missing a significant number of cases is considered unacceptable and subjecting healthy individuals to the repercussions of false-positive test results is also problematic. The decision to introduce a screening program also depends on the availability and cost of screening and diagnostic tests, the potential for testing to cause harm, the prevalence and prognosis of the condition, the availability of effective treatment, and the importance of presymptomatic treatment.
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:status
MEDLINE
pubmed:month
Jun
pubmed:issn
0095-5108
pubmed:author
pubmed:issnType
Print
pubmed:volume
30
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
189-204
pubmed:dateRevised
2005-11-16
pubmed:meshHeading
pubmed:year
2003
pubmed:articleTitle
Understanding and using diagnostic tests.
pubmed:affiliation
Department of Pediatrics, UT-Houston Medical School, 6431 Fannin, Suite 2.106, Houston, TX 77030, USA.
pubmed:publicationType
Journal Article, Review