Source:http://linkedlifedata.com/resource/pubmed/id/12875107
Switch to
Predicate | Object |
---|---|
rdf:type | |
lifeskim:mentions | |
pubmed:issue |
1
|
pubmed:dateCreated |
2003-7-23
|
pubmed:abstractText |
Exposure to saquinavir can be increased considerably by pharmacokinetic enhancement with ritonavir, without having a substantial impact on tolerability. Clinical trials indicate that both once-daily and twice-daily saquinavir/ritonavir treatment regimens, generally at dosages of 1,600 mg/100 mg once daily and 1,000 mg/100 mg twice daily, provide potent and sustained viral suppression and are well tolerated. In addition, data suggest that "double-boosting" strategies, including the combination of saquinavir with lopinavir/ritonavir, provide valuable treatment options in the salvage setting.
|
pubmed:language |
eng
|
pubmed:journal | |
pubmed:citationSubset |
IM
|
pubmed:chemical | |
pubmed:status |
MEDLINE
|
pubmed:issn |
1139-6121
|
pubmed:author | |
pubmed:issnType |
Print
|
pubmed:volume |
5
|
pubmed:owner |
NLM
|
pubmed:authorsComplete |
Y
|
pubmed:pagination |
44-51
|
pubmed:dateRevised |
2007-11-15
|
pubmed:meshHeading |
pubmed-meshheading:12875107-Clinical Trials as Topic,
pubmed-meshheading:12875107-Drug Therapy, Combination,
pubmed-meshheading:12875107-HIV Infections,
pubmed-meshheading:12875107-HIV Protease Inhibitors,
pubmed-meshheading:12875107-HIV-1,
pubmed-meshheading:12875107-Humans,
pubmed-meshheading:12875107-Ritonavir,
pubmed-meshheading:12875107-Saquinavir
|
pubmed:articleTitle |
Saquinavir/low-dose ritonavir: its use in HIV infection.
|
pubmed:affiliation |
Infection and Immunity Services, Royal Free Hospital, Pons Street, London NW3 2QG, UK. ma@johnson.u-net.com
|
pubmed:publicationType |
Journal Article,
Review
|