| pubmed-article:12874364 | rdf:type | pubmed:Citation | lld:pubmed |
| pubmed-article:12874364 | lifeskim:mentions | umls-concept:C0021758 | lld:lifeskim |
| pubmed-article:12874364 | lifeskim:mentions | umls-concept:C0123771 | lld:lifeskim |
| pubmed-article:12874364 | lifeskim:mentions | umls-concept:C0037083 | lld:lifeskim |
| pubmed-article:12874364 | lifeskim:mentions | umls-concept:C0441655 | lld:lifeskim |
| pubmed-article:12874364 | lifeskim:mentions | umls-concept:C0745754 | lld:lifeskim |
| pubmed-article:12874364 | lifeskim:mentions | umls-concept:C1710082 | lld:lifeskim |
| pubmed-article:12874364 | lifeskim:mentions | umls-concept:C1527148 | lld:lifeskim |
| pubmed-article:12874364 | lifeskim:mentions | umls-concept:C2003941 | lld:lifeskim |
| pubmed-article:12874364 | lifeskim:mentions | umls-concept:C1880177 | lld:lifeskim |
| pubmed-article:12874364 | lifeskim:mentions | umls-concept:C2698651 | lld:lifeskim |
| pubmed-article:12874364 | pubmed:issue | 8 | lld:pubmed |
| pubmed-article:12874364 | pubmed:dateCreated | 2003-7-22 | lld:pubmed |
| pubmed-article:12874364 | pubmed:abstractText | The roles of interleukin-4 (IL-4) and IL-13 in the regulation of immunity to Leishmania donovani infection are still poorly understood. Here we show that the increased parasite load observed in IL-4(-/-) and IL-4 receptor alpha(-/-) mice correlates with retarded granuloma maturation and antileishmanial activity and that the increased parasite load observed in IL-4 receptor alpha(-/-) mice correlates with increased NOS2 expression and decreased serum gamma interferon levels. IL-4 and IL-13 appear to play little role in regulating collagen deposition in L. donovani-induced granulomas. | lld:pubmed |
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| pubmed-article:12874364 | pubmed:language | eng | lld:pubmed |
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| pubmed-article:12874364 | pubmed:citationSubset | IM | lld:pubmed |
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| pubmed-article:12874364 | pubmed:status | MEDLINE | lld:pubmed |
| pubmed-article:12874364 | pubmed:month | Aug | lld:pubmed |
| pubmed-article:12874364 | pubmed:issn | 0019-9567 | lld:pubmed |
| pubmed-article:12874364 | pubmed:author | pubmed-author:BrombacherFra... | lld:pubmed |
| pubmed-article:12874364 | pubmed:author | pubmed-author:KayePaul MPM | lld:pubmed |
| pubmed-article:12874364 | pubmed:author | pubmed-author:AlexanderJame... | lld:pubmed |
| pubmed-article:12874364 | pubmed:author | pubmed-author:CarterK... | lld:pubmed |
| pubmed-article:12874364 | pubmed:author | pubmed-author:StägerSimonaS | lld:pubmed |
| pubmed-article:12874364 | pubmed:issnType | Print | lld:pubmed |
| pubmed-article:12874364 | pubmed:volume | 71 | lld:pubmed |
| pubmed-article:12874364 | pubmed:owner | NLM | lld:pubmed |
| pubmed-article:12874364 | pubmed:authorsComplete | Y | lld:pubmed |
| pubmed-article:12874364 | pubmed:pagination | 4804-7 | lld:pubmed |
| pubmed-article:12874364 | pubmed:dateRevised | 2009-11-18 | lld:pubmed |
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| pubmed-article:12874364 | pubmed:year | 2003 | lld:pubmed |
| pubmed-article:12874364 | pubmed:articleTitle | Both interleukin-4 (IL-4) and IL-4 receptor alpha signaling contribute to the development of hepatic granulomas with optimal antileishmanial activity. | lld:pubmed |
| pubmed-article:12874364 | pubmed:affiliation | Department of Infectious and Tropical Diseases, London School of Hygiene and Tropical Medicine, London, United Kingdom. | lld:pubmed |
| pubmed-article:12874364 | pubmed:publicationType | Journal Article | lld:pubmed |
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