Linked Life Data

12869134

Source:http://linkedlifedata.com/resource/pubmed/id/12869134

Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
2
pubmed:dateCreated
2003-7-18
pubmed:abstractText
During the differentiation process of B lymphocytes, they go through changes in adhesion and motility. In order to investigate the molecular mechanism of such changes, in vitro culture systems are necessary. When B cells are activated by various stimuli, they form different types of homotypic aggregates. In addition, they might also spread and express microvilli and/or become polarized, the latter being a sign of motility. In this review, we summarize our own research in this area. We give evidence for involvement of different adhesion and signalling molecules, and by the end, we speculate on the in vivo significance of our findings.
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:chemical
pubmed:status
MEDLINE
pubmed:month
Aug
pubmed:issn
0300-9475
pubmed:author
pubmed:issnType
Print
pubmed:volume
58
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
139-44
pubmed:dateRevised
2006-11-15
pubmed:meshHeading
pubmed:year
2003
pubmed:articleTitle
Regulation of adhesion and motility in B lymphocytes.
pubmed:affiliation
Department of Cell and Molecular Biology, Karolinska Institutet, Box 285, SE-171 77 Stockholm, Sweden. eva.severinson@cmb.ki.se
pubmed:publicationType
Journal Article, Review, Research Support, Non-U.S. Gov't