|
rdf:type |
|
|
lifeskim:mentions |
umls-concept:C0013455,
umls-concept:C0031437,
umls-concept:C0033105,
umls-concept:C0038410,
umls-concept:C0041703,
umls-concept:C0205099,
umls-concept:C0282563,
umls-concept:C0370215,
umls-concept:C0683598,
umls-concept:C1441672,
umls-concept:C1521725
|
|
pubmed:issue |
7
|
|
pubmed:dateCreated |
2003-7-17
|
|
pubmed:abstractText |
Increasing macrolide resistance among middle ear isolates complicates treatment of otitis media in children. When macrolide resistance is mediated via an efflux pump (M phenotype), the MICs of erythromycin, clarithromycin and azithromycin are usually below 32 microg/ml, and the pneumococcus remains susceptible to clindamycin. The association of prior specific macrolide therapy with the isolation of a macrolide resistant strain has not been reported.
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|
pubmed:language |
eng
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|
pubmed:journal |
|
|
pubmed:citationSubset |
IM
|
|
pubmed:chemical |
|
|
pubmed:status |
MEDLINE
|
|
pubmed:month |
Jul
|
|
pubmed:issn |
0891-3668
|
|
pubmed:author |
|
|
pubmed:issnType |
Print
|
|
pubmed:volume |
22
|
|
pubmed:owner |
NLM
|
|
pubmed:authorsComplete |
Y
|
|
pubmed:pagination |
623-7
|
|
pubmed:dateRevised |
2006-11-15
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|
pubmed:meshHeading |
pubmed-meshheading:12867838-Anti-Bacterial Agents,
pubmed-meshheading:12867838-Child,
pubmed-meshheading:12867838-Child, Preschool,
pubmed-meshheading:12867838-Drug Resistance, Bacterial,
pubmed-meshheading:12867838-Drug Resistance, Multiple,
pubmed-meshheading:12867838-Ear, Middle,
pubmed-meshheading:12867838-Female,
pubmed-meshheading:12867838-Humans,
pubmed-meshheading:12867838-Infant,
pubmed-meshheading:12867838-Macrolides,
pubmed-meshheading:12867838-Male,
pubmed-meshheading:12867838-Microbial Sensitivity Tests,
pubmed-meshheading:12867838-Otitis Media,
pubmed-meshheading:12867838-Pharmacogenetics,
pubmed-meshheading:12867838-Phenotype,
pubmed-meshheading:12867838-Pneumococcal Infections,
pubmed-meshheading:12867838-Prevalence,
pubmed-meshheading:12867838-Retrospective Studies,
pubmed-meshheading:12867838-Sensitivity and Specificity,
pubmed-meshheading:12867838-Streptococcus pneumoniae,
pubmed-meshheading:12867838-United States
|
|
pubmed:year |
2003
|
|
pubmed:articleTitle |
Macrolide resistance among middle ear isolates of Streptococcus pneumoniae observed at eight United States pediatric centers: prevalence of M and MLSB phenotypes.
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|
pubmed:affiliation |
Baylor College of Medicine, Houston, TX, USA.
|
|
pubmed:publicationType |
Journal Article,
Comparative Study,
Research Support, Non-U.S. Gov't,
Multicenter Study
|
