Source:http://linkedlifedata.com/resource/pubmed/id/12866958
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Predicate | Object |
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rdf:type | |
lifeskim:mentions | |
pubmed:issue |
7
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pubmed:dateCreated |
2003-7-17
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pubmed:abstractText |
Previous study has demonstrated that high frequent gain of 1q was detected in hepatocellular carcinoma (HCC), 1q21-22 was identified as the minimum overlapping amplified region and might contain the candidate oncogenes involved in HCC. RIT1 gene is located in 1q21.3 region and is a member of Ras subfamily. RIT1 protein is similar to Ras protein in molecular structure and functions. It was speculated that RIT1 gene might be a candidate oncogene in HCC. So, the amplification of RIT1 gene was examined in HCC and was linked with the clinical indicators in this study to explore the possible functions of RIT1 gene in HCC development and progression.
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pubmed:language |
chi
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pubmed:journal | |
pubmed:citationSubset |
IM
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pubmed:chemical | |
pubmed:status |
MEDLINE
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pubmed:month |
Jul
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pubmed:issn |
1000-467X
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pubmed:author | |
pubmed:issnType |
Print
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pubmed:volume |
22
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
695-9
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pubmed:dateRevised |
2006-11-15
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pubmed:meshHeading |
pubmed-meshheading:12866958-Adult,
pubmed-meshheading:12866958-Aged,
pubmed-meshheading:12866958-Carcinoma, Hepatocellular,
pubmed-meshheading:12866958-Chromosomes, Human, Pair 1,
pubmed-meshheading:12866958-Female,
pubmed-meshheading:12866958-Gene Amplification,
pubmed-meshheading:12866958-Humans,
pubmed-meshheading:12866958-Liver Neoplasms,
pubmed-meshheading:12866958-Male,
pubmed-meshheading:12866958-Middle Aged,
pubmed-meshheading:12866958-Neoplasm Staging,
pubmed-meshheading:12866958-Polymerase Chain Reaction,
pubmed-meshheading:12866958-ras Proteins
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pubmed:year |
2003
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pubmed:articleTitle |
[Amplification of RIT1 in hepatocellular carcinoma and its clinical significance].
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pubmed:affiliation |
Cancer Institute, Cancer Center, Sun Yat-sen Univesity, Guangzhou, 510060, PR China. lijintian006@hotmail.com
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pubmed:publicationType |
Journal Article,
Research Support, U.S. Gov't, P.H.S.,
English Abstract
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