A new triterpene compound ( 1), along with arjunolic acid, was isolated from an ethanol extract of the whole plant of Leandra chaetodon. Based on spectroscopic analysis, the structure of 1 was determined as 2alpha,6alpha- dihydroxybetulinic acid. Arjunolic acid showed inhibitory activity against Cryptococcus neoformans. (IC50 = 20 micrograms/mL).
National Center for Natural Products Research, Research Institute of Pharmaceutical Sciences, Thad Cochran Research Center, School of Pharmacy, The University of Mississippi, University, MS, USA.
