12860725

Source:http://linkedlifedata.com/resource/pubmed/id/12860725

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Predicate	Object
rdf:type	pubmed:Citation
lifeskim:mentions	umls-concept:C0003873, umls-concept:C0012634, umls-concept:C0030705, umls-concept:C0178566, umls-concept:C0205191, umls-concept:C0282554, umls-concept:C0332206, umls-concept:C0333348
pubmed:issue	8
pubmed:dateCreated	2003-7-15
pubmed:abstractText	Chemokines and their receptors are considered important contributors in cell migration and inflammation in chronic inflammatory disorders. Chemokines affecting monocytes/macrophages are considered potential therapeutic targets, but no studies of the effects of blocking the chemokine repertoire in humans with a chronic inflammatory disease have been reported.
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pubmed:language	eng
pubmed:journal	http://linkedlifedata.com/resource/pubmed/journal/0372355
pubmed:citationSubset	IM
pubmed:chemical	http://linkedlifedata.com/resource/pubmed/chemical/Antigens, CD, http://linkedlifedata.com/resource/pubmed/chemical/Antigens, Differentiation..., http://linkedlifedata.com/resource/pubmed/chemical/Antirheumatic Agents, http://linkedlifedata.com/resource/pubmed/chemical/CCR1 protein, human, http://linkedlifedata.com/resource/pubmed/chemical/CD68 antigen, human, http://linkedlifedata.com/resource/pubmed/chemical/Receptors, CCR1, http://linkedlifedata.com/resource/pubmed/chemical/Receptors, Chemokine
pubmed:status	MEDLINE
pubmed:month	Aug
pubmed:issn	0003-4967
pubmed:author	pubmed-author:HaringmanJ JJJ, pubmed-author:KraanM CMC, pubmed-author:RaoR LRL, pubmed-author:SmeetsT J MTJ, pubmed-author:ZwindermanK HKH
pubmed:issnType	Print
pubmed:volume	62
pubmed:owner	NLM
pubmed:authorsComplete	Y
pubmed:pagination	715-21
pubmed:dateRevised	2009-11-18
pubmed:meshHeading	pubmed-meshheading:12860725-Adult, pubmed-meshheading:12860725-Aged, pubmed-meshheading:12860725-Antigens, CD, pubmed-meshheading:12860725-Antigens, Differentiation, Myelomonocytic, pubmed-meshheading:12860725-Antirheumatic Agents, pubmed-meshheading:12860725-Arthritis, Rheumatoid, pubmed-meshheading:12860725-CD4-Positive T-Lymphocytes, pubmed-meshheading:12860725-CD8-Positive T-Lymphocytes, pubmed-meshheading:12860725-Double-Blind Method, pubmed-meshheading:12860725-Female, pubmed-meshheading:12860725-Humans, pubmed-meshheading:12860725-Macrophages, pubmed-meshheading:12860725-Male, pubmed-meshheading:12860725-Middle Aged, pubmed-meshheading:12860725-Receptors, CCR1, pubmed-meshheading:12860725-Receptors, Chemokine, pubmed-meshheading:12860725-Synovial Membrane, pubmed-meshheading:12860725-Treatment Outcome
pubmed:year	2003
pubmed:articleTitle	Chemokine blockade and chronic inflammatory disease: proof of concept in patients with rheumatoid arthritis.
pubmed:affiliation	Division of Clinical Immunology and Rheumatology, Academic Medical Centre/University of Amsterdam, The Netherlands.
pubmed:publicationType	Journal Article, Clinical Trial, Randomized Controlled Trial, Research Support, Non-U.S. Gov't, Clinical Trial, Phase I