Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
2-3
pubmed:dateCreated
2003-7-15
pubmed:abstractText
Antioxidant activity of the aqueous (AET) and methanolic extracts (MET) of the Thespesia populnea bark was investigated in rats by inducing liver injury with carbon tetrachloride:olive oil (1:1). The extracts exhibited significant antioxidant activity showing increased levels of glutathione peroxidase (GPX), glutathione S-transferase (GST), glutathione reductase (GRD), superoxide dismutase (SOD) and catalase (CAT) and decreased level of lipid peroxidation (LPO). Thespesia populnea bark extracts, AET and MET, at a dose level of 500mg/kg showed significant antioxidant activity against carbon tetrachloride-induced liver injury in rats.
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:chemical
pubmed:status
MEDLINE
pubmed:month
Aug
pubmed:issn
0378-8741
pubmed:author
pubmed:issnType
Print
pubmed:volume
87
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
227-30
pubmed:dateRevised
2009-11-19
pubmed:meshHeading
pubmed-meshheading:12860313-Animals, pubmed-meshheading:12860313-Antioxidants, pubmed-meshheading:12860313-Carbon Tetrachloride Poisoning, pubmed-meshheading:12860313-Catalase, pubmed-meshheading:12860313-Drug-Induced Liver Injury, pubmed-meshheading:12860313-Female, pubmed-meshheading:12860313-Glutathione Peroxidase, pubmed-meshheading:12860313-Glutathione Reductase, pubmed-meshheading:12860313-Glutathione Transferase, pubmed-meshheading:12860313-Lipid Peroxidation, pubmed-meshheading:12860313-Liver, pubmed-meshheading:12860313-Male, pubmed-meshheading:12860313-Malvaceae, pubmed-meshheading:12860313-Methanol, pubmed-meshheading:12860313-Phytotherapy, pubmed-meshheading:12860313-Plant Bark, pubmed-meshheading:12860313-Plant Extracts, pubmed-meshheading:12860313-Rats, pubmed-meshheading:12860313-Rats, Wistar, pubmed-meshheading:12860313-Superoxide Dismutase, pubmed-meshheading:12860313-Water
pubmed:year
2003
pubmed:articleTitle
Antioxidant activity of Thespesia populnea bark extracts against carbon tetrachloride-induced liver injury in rats.
pubmed:affiliation
Department of Pharmacology, C. L. Baid Metha College of Pharmacy, Jyothi Nagar, Old Mahabalipuram Road, Thorapakkam, Chennai, 600096, India.
pubmed:publicationType
Journal Article