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rdf:type |
|
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lifeskim:mentions |
umls-concept:C0003501,
umls-concept:C0034804,
umls-concept:C0036429,
umls-concept:C0043210,
umls-concept:C0232970,
umls-concept:C0439849,
umls-concept:C0445223,
umls-concept:C0678951,
umls-concept:C1537647,
umls-concept:C1552599,
umls-concept:C1704787
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|
pubmed:issue |
2
|
|
pubmed:dateCreated |
2003-7-15
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|
pubmed:abstractText |
Aortic valvular sclerosis (AS) is an inflammatory process and not a result of normal ageing. The sclerotic process is accelerated by risk factors such as smoking and high cholesterol levels. The genetic factors for the development of AS are however unknown. Therefore the purpose of the present study was to investigate whether polymorphisms in the oestrogen receptor alpha (ORalpha) gene and in the transforming growth factor beta (TGF-beta1) gene were related to the presence of AS in postmenopausal women.
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pubmed:language |
eng
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pubmed:journal |
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pubmed:citationSubset |
IM
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pubmed:chemical |
|
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pubmed:status |
MEDLINE
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pubmed:month |
Aug
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pubmed:issn |
0954-6820
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pubmed:author |
|
|
pubmed:issnType |
Print
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pubmed:volume |
254
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
140-6
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pubmed:dateRevised |
2006-11-15
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pubmed:meshHeading |
pubmed-meshheading:12859695-Adolescent,
pubmed-meshheading:12859695-Aged,
pubmed-meshheading:12859695-Aged, 80 and over,
pubmed-meshheading:12859695-Analysis of Variance,
pubmed-meshheading:12859695-Aortic Valve Stenosis,
pubmed-meshheading:12859695-Case-Control Studies,
pubmed-meshheading:12859695-Estrogen Receptor alpha,
pubmed-meshheading:12859695-Female,
pubmed-meshheading:12859695-Genotype,
pubmed-meshheading:12859695-Humans,
pubmed-meshheading:12859695-Middle Aged,
pubmed-meshheading:12859695-Polymorphism, Genetic,
pubmed-meshheading:12859695-Postmenopause,
pubmed-meshheading:12859695-Receptors, Estrogen,
pubmed-meshheading:12859695-Restriction Mapping,
pubmed-meshheading:12859695-Risk Factors
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|
pubmed:year |
2003
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|
pubmed:articleTitle |
Oestrogen receptor alpha gene polymorphism is related to aortic valve sclerosis in postmenopausal women.
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pubmed:affiliation |
Sports Medicine Unit, Department of Perioperative Sciences, National Institute for Working Life, Umeå, Sweden. peter.nordstrom@idrott.umu.se
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pubmed:publicationType |
Journal Article,
Research Support, Non-U.S. Gov't
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