Source:http://linkedlifedata.com/resource/pubmed/id/12858078
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| Predicate | Object |
|---|---|
| rdf:type | |
| lifeskim:mentions | |
| pubmed:issue |
3
|
| pubmed:dateCreated |
2003-7-14
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| pubmed:abstractText |
Multiple sclerosis is a central nervous system inflammatory demyelinating disease that is thought to have an autoimmune pathogenesis. Recent results indicate that 'statins', 3-hydroxy-3-methylglutaryl coenzyme A reductase inhibitors, which are the most commonly used oral cholesterol-lowering drugs, have immunomodulatory properties. In this article we will review those findings that indicate that statins may be beneficial in the treatment of multiple sclerosis, neurodegenerative disease, and ischemic stroke.
|
| pubmed:grant | |
| pubmed:language |
eng
|
| pubmed:journal | |
| pubmed:citationSubset |
IM
|
| pubmed:chemical | |
| pubmed:status |
MEDLINE
|
| pubmed:month |
Jun
|
| pubmed:issn |
1350-7540
|
| pubmed:author | |
| pubmed:issnType |
Print
|
| pubmed:volume |
16
|
| pubmed:owner |
NLM
|
| pubmed:authorsComplete |
Y
|
| pubmed:pagination |
393-401
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| pubmed:dateRevised |
2007-11-15
|
| pubmed:meshHeading |
pubmed-meshheading:12858078-Alzheimer Disease,
pubmed-meshheading:12858078-Animals,
pubmed-meshheading:12858078-Brain Ischemia,
pubmed-meshheading:12858078-Central Nervous System,
pubmed-meshheading:12858078-Humans,
pubmed-meshheading:12858078-Hydroxymethylglutaryl-CoA Reductase Inhibitors,
pubmed-meshheading:12858078-Inflammation,
pubmed-meshheading:12858078-Leukocytes,
pubmed-meshheading:12858078-Multiple Sclerosis,
pubmed-meshheading:12858078-Neurodegenerative Diseases,
pubmed-meshheading:12858078-Stroke
|
| pubmed:year |
2003
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| pubmed:articleTitle |
Statins as potential therapeutic agents in neuroinflammatory disorders.
|
| pubmed:affiliation |
Department of Neurology, University of California, San Francisco, California 94143, USA.
|
| pubmed:publicationType |
Journal Article,
Research Support, U.S. Gov't, P.H.S.,
Review,
Research Support, Non-U.S. Gov't
|