Linked Life Data

1285586

Source:http://linkedlifedata.com/resource/pubmed/id/1285586

Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
9
pubmed:dateCreated
1993-3-11
pubmed:abstractText
Recently, we have demonstrated the presence of C3dg deposits, a cleavage fragment of the third component of complement, on the basement membrane zone (MB) of normal human skin. These C3dg deposits are specific, isolated and not restricted to stratified squamous epithelia. Their origin is not thought to be due to passive incorporation of circulating C3dg within selected MB. Conversely, human keratinocytes are able to synthesize and secrete C3 and could represent a local source for these C3dg deposits. In situ production of C3 by epidermal cells could play a role in local inflammatory reactions. Similarly, a C3dg binding site(s) in selected basement membrane may account for the accumulation of C3-containing immune complexes in such tissues in pathological conditions.
pubmed:commentsCorrections
pubmed:language
fre
pubmed:journal
pubmed:citationSubset
IM
pubmed:chemical
pubmed:status
MEDLINE
pubmed:issn
0151-9638
pubmed:author
pubmed:issnType
Print
pubmed:volume
119
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
629-34
pubmed:dateRevised
2006-11-15
pubmed:meshHeading
pubmed:year
1992
pubmed:articleTitle
[Cleavage fragments of C3 and of dermo-epidermal junction of normal human skin].
pubmed:affiliation
Laboratoire de Dermatologie moléculaire, Université de Montpellier I, France.
pubmed:publicationType
Journal Article, English Abstract, Review, Research Support, Non-U.S. Gov't