Source:http://linkedlifedata.com/resource/pubmed/id/12855813
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rdf:type | |
lifeskim:mentions | |
pubmed:issue |
5630
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pubmed:dateCreated |
2003-7-11
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pubmed:abstractText |
Choosing an action that leads to a desired goal requires an understanding of the linkages between actions and their outcomes. We investigated neural mechanisms of such goal-based action selection. We trained monkeys on a task in which the relation between visual cues, action types, and reward conditions changed regularly, such that the monkeys selected their actions based on anticipated reward conditions. A significant number of neurons in the medial prefrontal cortex were activated, after cue presentation and before motor execution, only by particular action-reward combinations. This prefrontal activity is likely to underlie goal-based action selection.
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pubmed:commentsCorrections | |
pubmed:language |
eng
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pubmed:journal | |
pubmed:citationSubset |
IM
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pubmed:status |
MEDLINE
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pubmed:month |
Jul
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pubmed:issn |
1095-9203
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pubmed:author | |
pubmed:issnType |
Electronic
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pubmed:day |
11
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pubmed:volume |
301
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
229-32
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pubmed:dateRevised |
2007-3-19
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pubmed:meshHeading |
pubmed-meshheading:12855813-Action Potentials,
pubmed-meshheading:12855813-Analysis of Variance,
pubmed-meshheading:12855813-Animals,
pubmed-meshheading:12855813-Brain Mapping,
pubmed-meshheading:12855813-Conditioning (Psychology),
pubmed-meshheading:12855813-Cues,
pubmed-meshheading:12855813-Decision Making,
pubmed-meshheading:12855813-Goals,
pubmed-meshheading:12855813-Haplorhini,
pubmed-meshheading:12855813-Learning,
pubmed-meshheading:12855813-Memory,
pubmed-meshheading:12855813-Neurons,
pubmed-meshheading:12855813-Prefrontal Cortex,
pubmed-meshheading:12855813-Psychomotor Performance,
pubmed-meshheading:12855813-Reward
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pubmed:year |
2003
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pubmed:articleTitle |
Neuronal correlates of goal-based motor selection in the prefrontal cortex.
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pubmed:affiliation |
Cognitive Brain Mapping Laboratory, RIKEN Brain Science Institute, 2-1 Hirosawa, Wako, Saitama 351-0198, Japan. matsumot@postman.riken.go.jp
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pubmed:publicationType |
Journal Article
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