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pubmed-article:12855612pubmed:abstractTextThe purpose of this study was to determine whether comprehensive transcriptional profiles (TPs) can be obtained from single-passage fine-needle aspirations (FNAs) of breast cancer and to explore whether profiles capture routine clinicopathological parameters. Experimental Design: Expression profiles were available on 38 patients with stage I-III breast cancer who underwent FNA at the time of diagnosis. [(33)P]dCTP-labeled cDNA probes were generated and hybridized to cDNA membrane microarrays that contained 30,000 human sequence clones, including 10,890 expressed sequence tags.lld:pubmed
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pubmed-article:12855612pubmed:articleTitleGene expression profiles obtained from fine-needle aspirations of breast cancer reliably identify routine prognostic markers and reveal large-scale molecular differences between estrogen-negative and estrogen-positive tumors.lld:pubmed
pubmed-article:12855612pubmed:affiliationDepartments of Breast Medical Oncology, The University of Texas M. D. Anderson Cancer Center, Houston, Texas 77030-009, USA. lpusztai@mdanderson.orglld:pubmed
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