|
rdf:type |
|
|
lifeskim:mentions |
umls-concept:C0006142,
umls-concept:C0027651,
umls-concept:C0191846,
umls-concept:C0205547,
umls-concept:C1301820,
umls-concept:C1510483,
umls-concept:C1514475,
umls-concept:C1521991,
umls-concept:C1705241,
umls-concept:C1705242,
umls-concept:C1956267
|
|
pubmed:issue |
7
|
|
pubmed:dateCreated |
2003-7-11
|
|
pubmed:abstractText |
The purpose of this study was to determine whether comprehensive transcriptional profiles (TPs) can be obtained from single-passage fine-needle aspirations (FNAs) of breast cancer and to explore whether profiles capture routine clinicopathological parameters. Experimental Design: Expression profiles were available on 38 patients with stage I-III breast cancer who underwent FNA at the time of diagnosis. [(33)P]dCTP-labeled cDNA probes were generated and hybridized to cDNA membrane microarrays that contained 30,000 human sequence clones, including 10,890 expressed sequence tags.
|
|
pubmed:language |
eng
|
|
pubmed:journal |
|
|
pubmed:citationSubset |
IM
|
|
pubmed:chemical |
|
|
pubmed:status |
MEDLINE
|
|
pubmed:month |
Jul
|
|
pubmed:issn |
1078-0432
|
|
pubmed:author |
pubmed-author:AdamsConstantineC,
pubmed-author:ArunBanuB,
pubmed-author:AyersMarkM,
pubmed-author:BooserDanielD,
pubmed-author:BuchholzThomas ATA,
pubmed-author:ClarkEdwardE,
pubmed-author:CristofanilliMassimoM,
pubmed-author:DamokoshAndrewA,
pubmed-author:EstevaFrancisco JFJ,
pubmed-author:HessKennethK,
pubmed-author:HortobagyiGabriel NGN,
pubmed-author:PusztaiLajosL,
pubmed-author:RosalesMargueriteM,
pubmed-author:SneigeNourN,
pubmed-author:StecJamesJ,
pubmed-author:StiversDavidD,
pubmed-author:SymmansW FraserWF,
pubmed-author:ValeroVicenteV
|
|
pubmed:issnType |
Print
|
|
pubmed:volume |
9
|
|
pubmed:owner |
NLM
|
|
pubmed:authorsComplete |
Y
|
|
pubmed:pagination |
2406-15
|
|
pubmed:dateRevised |
2009-11-19
|
|
pubmed:meshHeading |
pubmed-meshheading:12855612-Adult,
pubmed-meshheading:12855612-Aged,
pubmed-meshheading:12855612-Biopsy, Fine-Needle,
pubmed-meshheading:12855612-Breast Neoplasms,
pubmed-meshheading:12855612-Cluster Analysis,
pubmed-meshheading:12855612-DNA, Complementary,
pubmed-meshheading:12855612-Estrogens,
pubmed-meshheading:12855612-Female,
pubmed-meshheading:12855612-Gene Expression Regulation, Neoplastic,
pubmed-meshheading:12855612-Humans,
pubmed-meshheading:12855612-Immunohistochemistry,
pubmed-meshheading:12855612-In Situ Hybridization, Fluorescence,
pubmed-meshheading:12855612-Middle Aged,
pubmed-meshheading:12855612-Oligonucleotide Array Sequence Analysis,
pubmed-meshheading:12855612-Prognosis,
pubmed-meshheading:12855612-RNA,
pubmed-meshheading:12855612-RNA, Messenger,
pubmed-meshheading:12855612-Receptor, erbB-2,
pubmed-meshheading:12855612-Receptors, Estrogen,
pubmed-meshheading:12855612-Signal Transduction,
pubmed-meshheading:12855612-Time Factors
|
|
pubmed:year |
2003
|
|
pubmed:articleTitle |
Gene expression profiles obtained from fine-needle aspirations of breast cancer reliably identify routine prognostic markers and reveal large-scale molecular differences between estrogen-negative and estrogen-positive tumors.
|
|
pubmed:affiliation |
Departments of Breast Medical Oncology, The University of Texas M. D. Anderson Cancer Center, Houston, Texas 77030-009, USA. lpusztai@mdanderson.org
|
|
pubmed:publicationType |
Journal Article
|
