rdf:type |
|
lifeskim:mentions |
|
pubmed:issue |
9
|
pubmed:dateCreated |
2003-9-15
|
pubmed:abstractText |
Tissue factor (TF) is the main activator of the coagulation cascade occurring in physiologic and pathologic conditions. Recent data suggest that human platelets might contain TF that is possibly derived from leukocytes. In this study, we investigated whether intraplatelet TF can be exposed on the membrane by platelet agonists. The modulation of this process by antiplatelet drugs has been evaluated as well.
|
pubmed:language |
eng
|
pubmed:journal |
|
pubmed:citationSubset |
IM
|
pubmed:chemical |
|
pubmed:status |
MEDLINE
|
pubmed:month |
Sep
|
pubmed:issn |
1524-4636
|
pubmed:author |
pubmed-author:BonziRobertoR,
pubmed-author:BrambillaMartaM,
pubmed-author:CameraMarinaM,
pubmed-author:CottellDavid CDC,
pubmed-author:De VincentiOmbrettaO,
pubmed-author:FrigerioMartaM,
pubmed-author:MadernaPaolaP,
pubmed-author:ParolariAlessandroA,
pubmed-author:RossiFrancescaF,
pubmed-author:ToschiVincenzoV,
pubmed-author:TremoliElenaE
|
pubmed:issnType |
Electronic
|
pubmed:day |
1
|
pubmed:volume |
23
|
pubmed:owner |
NLM
|
pubmed:authorsComplete |
Y
|
pubmed:pagination |
1690-6
|
pubmed:dateRevised |
2006-11-15
|
pubmed:meshHeading |
pubmed-meshheading:12855480-Antigens, Surface,
pubmed-meshheading:12855480-Blood Platelets,
pubmed-meshheading:12855480-Humans,
pubmed-meshheading:12855480-Microscopy, Electron,
pubmed-meshheading:12855480-Platelet Activation,
pubmed-meshheading:12855480-Platelet Aggregation Inhibitors,
pubmed-meshheading:12855480-RNA, Messenger,
pubmed-meshheading:12855480-Thromboplastin
|
pubmed:year |
2003
|
pubmed:articleTitle |
Platelet activation induces cell-surface immunoreactive tissue factor expression, which is modulated differently by antiplatelet drugs.
|
pubmed:affiliation |
Department of Pharmacological Sciences, University of Milan, Italy.
|
pubmed:publicationType |
Journal Article,
Research Support, Non-U.S. Gov't
|