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rdf:type |
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lifeskim:mentions |
|
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pubmed:issue |
3
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pubmed:dateCreated |
1994-10-20
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pubmed:abstractText |
All of the patients with Wegener's granulomatosis (WG), whom we studied, exhibited abnormalities in lymphocyte subsets. We used two-color immunofluorescence flow cytometry to examine the lymphocyte subset alterations. WG group showed a decrease in the percentage of CD4+ cells and an increase of CD8+ cells. Within the NK cell family, functionally unidentified CD8+57+ cells were markedly increased in number. The disproportion of these lymphocyte subsets (CD4+ decreases, CD8+57+ increases) was similar to that seen in Acquired Immunodeficiency Syndrome (AIDS) and AIDS related complex (ARC).
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pubmed:language |
eng
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pubmed:journal |
|
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pubmed:citationSubset |
IM
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pubmed:chemical |
|
|
pubmed:status |
MEDLINE
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pubmed:issn |
0141-2760
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pubmed:author |
|
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pubmed:issnType |
Print
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pubmed:volume |
38
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
103-9
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pubmed:dateRevised |
2006-11-15
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pubmed:meshHeading |
pubmed-meshheading:1285384-Adult,
pubmed-meshheading:1285384-Antibodies, Monoclonal,
pubmed-meshheading:1285384-Antigens, CD,
pubmed-meshheading:1285384-Antigens, CD57,
pubmed-meshheading:1285384-Antigens, Differentiation, T-Lymphocyte,
pubmed-meshheading:1285384-CD4-CD8 Ratio,
pubmed-meshheading:1285384-CD4-Positive T-Lymphocytes,
pubmed-meshheading:1285384-Female,
pubmed-meshheading:1285384-Flow Cytometry,
pubmed-meshheading:1285384-Humans,
pubmed-meshheading:1285384-Immunophenotyping,
pubmed-meshheading:1285384-Killer Cells, Natural,
pubmed-meshheading:1285384-Male,
pubmed-meshheading:1285384-Middle Aged,
pubmed-meshheading:1285384-T-Lymphocytes, Regulatory,
pubmed-meshheading:1285384-Wegener Granulomatosis
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pubmed:year |
1992
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pubmed:articleTitle |
Reduced CD4-CD8 T cell ratios in patients with Wegener's granulomatosis.
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pubmed:affiliation |
Department of Microbiology, National Defense Medical College, Saitama, Japan.
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pubmed:publicationType |
Journal Article
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