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pubmed-article:12852964pubmed:abstractTextA solid-phase approach for the total synthesis of methyl carboxymycobactins 1a-d, with an on-resin cyclization leading to azopine 5 as the key step, was developed. The iron-affinity of these compounds was assessed by a competitive sulfoxine-binding assay, and antimycobacterial activity was tested against the growth of Mycobacterium avium.lld:pubmed
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pubmed-article:12852964pubmed:dateRevised2007-11-14lld:pubmed
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pubmed-article:12852964pubmed:articleTitleSolid-phase synthesis of methyl carboxymycobactin T 7 and analogues as potential antimycobacterial agents.lld:pubmed
pubmed-article:12852964pubmed:affiliationMetaPhore Pharmaceuticals, Inc., 1910 Innerbelt Business Center Drive, Saint Louis, MO 63114, USA.lld:pubmed
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pubmed-article:12852964pubmed:publicationTypeResearch Support, U.S. Gov't, P.H.S.lld:pubmed