| pubmed-article:12851400 | rdf:type | pubmed:Citation | lld:pubmed |
| pubmed-article:12851400 | lifeskim:mentions | umls-concept:C0019704 | lld:lifeskim |
| pubmed-article:12851400 | lifeskim:mentions | umls-concept:C0205147 | lld:lifeskim |
| pubmed-article:12851400 | lifeskim:mentions | umls-concept:C0035668 | lld:lifeskim |
| pubmed-article:12851400 | lifeskim:mentions | umls-concept:C1420569 | lld:lifeskim |
| pubmed-article:12851400 | lifeskim:mentions | umls-concept:C1420570 | lld:lifeskim |
| pubmed-article:12851400 | lifeskim:mentions | umls-concept:C1420571 | lld:lifeskim |
| pubmed-article:12851400 | lifeskim:mentions | umls-concept:C1145667 | lld:lifeskim |
| pubmed-article:12851400 | lifeskim:mentions | umls-concept:C0220903 | lld:lifeskim |
| pubmed-article:12851400 | lifeskim:mentions | umls-concept:C2242140 | lld:lifeskim |
| pubmed-article:12851400 | pubmed:issue | 41 | lld:pubmed |
| pubmed-article:12851400 | pubmed:dateCreated | 2003-10-6 | lld:pubmed |
| pubmed-article:12851400 | pubmed:abstractText | The leader RNA sequence of human immunodeficiency virus type 1 (HIV-1) consists of a complex series of stem loop structures that are critical for viral replication. Three-dimensional structural analysis by NMR of one of these structures, the SL1 stem loop of the packaging signal region, revealed a highly conserved purine rich loop with a structure nearly identical to the Rev-binding loop of the Rev response element. Using band-shift assays, surface plasmon resonance, and further NMR analysis, we demonstrate that this loop binds Rev. HIV-1 appears to have a second Rev-binding site close to the major splice donor site that may have an additional role in the viral life cycle. | lld:pubmed |
| pubmed-article:12851400 | pubmed:grant | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:12851400 | pubmed:language | eng | lld:pubmed |
| pubmed-article:12851400 | pubmed:journal | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:12851400 | pubmed:citationSubset | IM | lld:pubmed |
| pubmed-article:12851400 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:12851400 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:12851400 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:12851400 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:12851400 | pubmed:status | MEDLINE | lld:pubmed |
| pubmed-article:12851400 | pubmed:month | Oct | lld:pubmed |
| pubmed-article:12851400 | pubmed:issn | 0021-9258 | lld:pubmed |
| pubmed-article:12851400 | pubmed:author | pubmed-author:VyasSS | lld:pubmed |
| pubmed-article:12851400 | pubmed:author | pubmed-author:PomerantzRoge... | lld:pubmed |
| pubmed-article:12851400 | pubmed:author | pubmed-author:ZhangHuiH | lld:pubmed |
| pubmed-article:12851400 | pubmed:author | pubmed-author:FangJianhuaJ | lld:pubmed |
| pubmed-article:12851400 | pubmed:author | pubmed-author:LeverAndrew... | lld:pubmed |
| pubmed-article:12851400 | pubmed:author | pubmed-author:GreatorexJane... | lld:pubmed |
| pubmed-article:12851400 | pubmed:author | pubmed-author:LeaSusanS | lld:pubmed |
| pubmed-article:12851400 | pubmed:author | pubmed-author:GallegoJoseJ | lld:pubmed |
| pubmed-article:12851400 | pubmed:author | pubmed-author:ArunachalamSh... | lld:pubmed |
| pubmed-article:12851400 | pubmed:author | pubmed-author:SeamonsJohnJ | lld:pubmed |
| pubmed-article:12851400 | pubmed:issnType | Print | lld:pubmed |
| pubmed-article:12851400 | pubmed:day | 10 | lld:pubmed |
| pubmed-article:12851400 | pubmed:volume | 278 | lld:pubmed |
| pubmed-article:12851400 | pubmed:owner | NLM | lld:pubmed |
| pubmed-article:12851400 | pubmed:authorsComplete | Y | lld:pubmed |
| pubmed-article:12851400 | pubmed:pagination | 40385-91 | lld:pubmed |
| pubmed-article:12851400 | pubmed:dateRevised | 2007-11-15 | lld:pubmed |
| pubmed-article:12851400 | pubmed:meshHeading | pubmed-meshheading:12851400... | lld:pubmed |
| pubmed-article:12851400 | pubmed:meshHeading | pubmed-meshheading:12851400... | lld:pubmed |
| pubmed-article:12851400 | pubmed:meshHeading | pubmed-meshheading:12851400... | lld:pubmed |
| pubmed-article:12851400 | pubmed:meshHeading | pubmed-meshheading:12851400... | lld:pubmed |
| pubmed-article:12851400 | pubmed:meshHeading | pubmed-meshheading:12851400... | lld:pubmed |
| pubmed-article:12851400 | pubmed:meshHeading | pubmed-meshheading:12851400... | lld:pubmed |
| pubmed-article:12851400 | pubmed:meshHeading | pubmed-meshheading:12851400... | lld:pubmed |
| pubmed-article:12851400 | pubmed:meshHeading | pubmed-meshheading:12851400... | lld:pubmed |
| pubmed-article:12851400 | pubmed:meshHeading | pubmed-meshheading:12851400... | lld:pubmed |
| pubmed-article:12851400 | pubmed:meshHeading | pubmed-meshheading:12851400... | lld:pubmed |
| pubmed-article:12851400 | pubmed:meshHeading | pubmed-meshheading:12851400... | lld:pubmed |
| pubmed-article:12851400 | pubmed:meshHeading | pubmed-meshheading:12851400... | lld:pubmed |
| pubmed-article:12851400 | pubmed:meshHeading | pubmed-meshheading:12851400... | lld:pubmed |
| pubmed-article:12851400 | pubmed:meshHeading | pubmed-meshheading:12851400... | lld:pubmed |
| pubmed-article:12851400 | pubmed:meshHeading | pubmed-meshheading:12851400... | lld:pubmed |
| pubmed-article:12851400 | pubmed:year | 2003 | lld:pubmed |
| pubmed-article:12851400 | pubmed:articleTitle | Rev binds specifically to a purine loop in the SL1 region of the HIV-1 leader RNA. | lld:pubmed |
| pubmed-article:12851400 | pubmed:affiliation | Medical Research Council Laboratory of Molecular Biology, Hills Road, Cambridge CB2 2QH, United Kingdom. | lld:pubmed |
| pubmed-article:12851400 | pubmed:publicationType | Journal Article | lld:pubmed |
| pubmed-article:12851400 | pubmed:publicationType | In Vitro | lld:pubmed |
| pubmed-article:12851400 | pubmed:publicationType | Research Support, U.S. Gov't, P.H.S. | lld:pubmed |
| pubmed-article:12851400 | pubmed:publicationType | Research Support, Non-U.S. Gov't | lld:pubmed |
| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:12851400 | lld:pubmed |
| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:12851400 | lld:pubmed |
| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:12851400 | lld:pubmed |
| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:12851400 | lld:pubmed |
| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:12851400 | lld:pubmed |
| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:12851400 | lld:pubmed |
