rdf:type |
|
lifeskim:mentions |
|
pubmed:issue |
2
|
pubmed:dateCreated |
2003-7-9
|
pubmed:abstractText |
Interleukin 6 (IL-6) is elevated in the arterial wall in atherosclerosis and restenosis after angioplasty. An important contributor to these pathologies is migration of vascular smooth muscle cells (VSMC), which is often associated with cytoskeletal reorganization initiated by growth factors and chemokines. We recently reported that IL-6 stimulated migration of VSMC. Here, we examined the cytoskeleton of VSMC and cytoskeletal associated proteins to determine potential mechanisms associated with IL-6 induced migration.
|
pubmed:language |
eng
|
pubmed:journal |
|
pubmed:citationSubset |
IM
|
pubmed:chemical |
http://linkedlifedata.com/resource/pubmed/chemical/Actins,
http://linkedlifedata.com/resource/pubmed/chemical/Cytochalasin D,
http://linkedlifedata.com/resource/pubmed/chemical/Cytoskeletal Proteins,
http://linkedlifedata.com/resource/pubmed/chemical/Focal Adhesion Kinase 1,
http://linkedlifedata.com/resource/pubmed/chemical/Focal Adhesion Protein-Tyrosine...,
http://linkedlifedata.com/resource/pubmed/chemical/Interleukin-6,
http://linkedlifedata.com/resource/pubmed/chemical/Paxillin,
http://linkedlifedata.com/resource/pubmed/chemical/Phosphoproteins,
http://linkedlifedata.com/resource/pubmed/chemical/Phosphotyrosine,
http://linkedlifedata.com/resource/pubmed/chemical/Polymers,
http://linkedlifedata.com/resource/pubmed/chemical/Protein-Tyrosine Kinases,
http://linkedlifedata.com/resource/pubmed/chemical/Ptk2 protein, rat,
http://linkedlifedata.com/resource/pubmed/chemical/Pxn protein, rat
|
pubmed:status |
MEDLINE
|
pubmed:month |
May
|
pubmed:issn |
0022-4804
|
pubmed:author |
|
pubmed:issnType |
Print
|
pubmed:day |
15
|
pubmed:volume |
111
|
pubmed:owner |
NLM
|
pubmed:authorsComplete |
Y
|
pubmed:pagination |
261-6
|
pubmed:dateRevised |
2009-11-19
|
pubmed:meshHeading |
pubmed-meshheading:12850472-Actins,
pubmed-meshheading:12850472-Animals,
pubmed-meshheading:12850472-Aorta, Thoracic,
pubmed-meshheading:12850472-Cell Movement,
pubmed-meshheading:12850472-Cells, Cultured,
pubmed-meshheading:12850472-Cytochalasin D,
pubmed-meshheading:12850472-Cytoskeletal Proteins,
pubmed-meshheading:12850472-Cytoskeleton,
pubmed-meshheading:12850472-Focal Adhesion Kinase 1,
pubmed-meshheading:12850472-Focal Adhesion Protein-Tyrosine Kinases,
pubmed-meshheading:12850472-Interleukin-6,
pubmed-meshheading:12850472-Male,
pubmed-meshheading:12850472-Muscle, Smooth, Vascular,
pubmed-meshheading:12850472-Paxillin,
pubmed-meshheading:12850472-Phosphoproteins,
pubmed-meshheading:12850472-Phosphorylation,
pubmed-meshheading:12850472-Phosphotyrosine,
pubmed-meshheading:12850472-Polymers,
pubmed-meshheading:12850472-Protein-Tyrosine Kinases,
pubmed-meshheading:12850472-Rats,
pubmed-meshheading:12850472-Rats, Sprague-Dawley
|
pubmed:year |
2003
|
pubmed:articleTitle |
Smooth muscle cell migration stimulated by interleukin 6 is associated with cytoskeletal reorganization.
|
pubmed:affiliation |
Division of Basic Medical Science and Department of Anesthesiology, Mercer Universtiy School of Medicine and Medical Center of Central Georgia, Macon, 31207, USA. wang_z@mercer.edu
|
pubmed:publicationType |
Journal Article,
Research Support, Non-U.S. Gov't
|