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rdf:type |
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lifeskim:mentions |
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pubmed:issue |
6
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pubmed:dateCreated |
1993-6-7
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pubmed:databankReference |
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pubmed:abstractText |
cDNA clones for a human HOX 7 gene obtained with homologous clones of Drosophila were used in human gene mapping studies. The human cDNA clone was isolated from a library constructed from human embryonic craniofacial material. The sequence of the cDNA demonstrates significant homology with mouse HOX 7. A search for RFLPs identified MboII and BstEII variants. A CA dinucleotide repeat with 5 alleles was also identified and allowed placement of HOX 7 into a defined linkage map. Evidence for linkage disequilibrium was found with markers tested. These results place the human HOX 7 gene in a defined position on 4p.
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pubmed:grant |
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pubmed:language |
eng
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pubmed:journal |
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pubmed:citationSubset |
IM
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pubmed:chemical |
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pubmed:status |
MEDLINE
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pubmed:month |
Sep
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pubmed:issn |
0964-6906
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pubmed:author |
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pubmed:issnType |
Print
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pubmed:volume |
1
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pubmed:geneSymbol |
HOX 7,
msh
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
407-10
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pubmed:dateRevised |
2008-11-21
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pubmed:meshHeading |
pubmed-meshheading:1284527-Amino Acid Sequence,
pubmed-meshheading:1284527-Animals,
pubmed-meshheading:1284527-Base Sequence,
pubmed-meshheading:1284527-Chromosome Mapping,
pubmed-meshheading:1284527-Chromosomes, Human, Pair 4,
pubmed-meshheading:1284527-Cloning, Molecular,
pubmed-meshheading:1284527-DNA,
pubmed-meshheading:1284527-Deoxyribonucleases, Type II Site-Specific,
pubmed-meshheading:1284527-Drosophila,
pubmed-meshheading:1284527-Embryo, Mammalian,
pubmed-meshheading:1284527-Embryo, Nonmammalian,
pubmed-meshheading:1284527-Female,
pubmed-meshheading:1284527-Gene Library,
pubmed-meshheading:1284527-Genes, Homeobox,
pubmed-meshheading:1284527-Genetic Variation,
pubmed-meshheading:1284527-Humans,
pubmed-meshheading:1284527-Linkage Disequilibrium,
pubmed-meshheading:1284527-Male,
pubmed-meshheading:1284527-Molecular Sequence Data,
pubmed-meshheading:1284527-Oligodeoxyribonucleotides,
pubmed-meshheading:1284527-Pedigree,
pubmed-meshheading:1284527-Polymorphism, Restriction Fragment Length,
pubmed-meshheading:1284527-RNA,
pubmed-meshheading:1284527-Restriction Mapping,
pubmed-meshheading:1284527-Sequence Homology, Nucleic Acid
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pubmed:year |
1992
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pubmed:articleTitle |
Characterization of the human HOX 7 cDNA and identification of polymorphic markers.
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pubmed:affiliation |
Department of Biology, University of Iowa, Iowa City 52242.
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pubmed:publicationType |
Journal Article,
Research Support, U.S. Gov't, P.H.S.
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