rdf:type |
|
lifeskim:mentions |
|
pubmed:issue |
7
|
pubmed:dateCreated |
2003-7-4
|
pubmed:abstractText |
1-(11)C-Octanoate is a potential tracer for studying astroglial function in PET. To evaluate the usefulness of 1-(11)C-octanoate for studying ischemic stroke, we investigated the brain distribution of 1-(14)C-octanoate and compared it with N-isopropyl-p-(123)I-iodoamphetamine ((123)I-IMP) distribution (cerebral blood flow), (123)I-iomazenil ((123)I-IMZ) distribution (neuronal viability based on (123)I-IMZ binding to benzodiazepine receptors), and hematoxylin-eosin stain (morphologic changes) in a rat model of focal cerebral ischemia.
|
pubmed:language |
eng
|
pubmed:journal |
|
pubmed:citationSubset |
IM
|
pubmed:chemical |
|
pubmed:status |
MEDLINE
|
pubmed:month |
Jul
|
pubmed:issn |
0161-5505
|
pubmed:author |
|
pubmed:issnType |
Print
|
pubmed:volume |
44
|
pubmed:owner |
NLM
|
pubmed:authorsComplete |
Y
|
pubmed:pagination |
1168-75
|
pubmed:dateRevised |
2006-11-15
|
pubmed:meshHeading |
pubmed-meshheading:12843233-Animals,
pubmed-meshheading:12843233-Autoradiography,
pubmed-meshheading:12843233-Brain,
pubmed-meshheading:12843233-Brain Ischemia,
pubmed-meshheading:12843233-Disease Models, Animal,
pubmed-meshheading:12843233-Flumazenil,
pubmed-meshheading:12843233-Iofetamine,
pubmed-meshheading:12843233-Octanoic Acids,
pubmed-meshheading:12843233-Radiopharmaceuticals,
pubmed-meshheading:12843233-Rats,
pubmed-meshheading:12843233-Rats, Sprague-Dawley,
pubmed-meshheading:12843233-Tissue Distribution
|
pubmed:year |
2003
|
pubmed:articleTitle |
Characteristic brain distribution of 1-(14)C-octanoate in a rat model of focal cerebral ischemia in comparison with those of (123)I-IMP and (123)I-iomazenil.
|
pubmed:affiliation |
Departments of Tracer Kinetics and Nuclear Medicine, Graduate School of Medicine, Hokkaido University, Sapporo, Japan. kuge@med.hokudai.ac.jp
|
pubmed:publicationType |
Journal Article,
Comparative Study,
Research Support, Non-U.S. Gov't,
Evaluation Studies,
Validation Studies
|