Linked Life Data

12842846

Source:http://linkedlifedata.com/resource/pubmed/id/12842846

Statements in which the resource exists.
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pubmed-article:12842846pubmed:abstractTextNeointima formation occurs in arteries in response to mechanical or chemical injury and is responsible for substantial morbidity. In this work, the role of the intracellular linker protein Grb2 in the pathogenesis of neointima formation was examined. Grb2 is a critical signaling protein that facilitates the activation of the small GTPase ras by receptor tyrosine kinases.lld:pubmed
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pubmed-article:12842846pubmed:articleTitleGrb2 is required for the development of neointima in response to vascular injury.lld:pubmed
pubmed-article:12842846pubmed:affiliationCenter for Cardiovascular Research, Department of Medicine, Washington University School of Medicine, St. Louis, MO, USA.lld:pubmed
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