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rdf:type |
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|
lifeskim:mentions |
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|
pubmed:issue |
11-12
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pubmed:dateCreated |
1993-4-22
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|
pubmed:abstractText |
It has been established that preliminary administration of D-Ala2-Leu5-Arg6-enkephalin, D-Met2-Pro5-enkephalinamide, and D-phenylalanine to experimental animals prevents a stress-induced increase of the content of thromboxane in the blood plasma and myocardium and induces a rise of the level of prostacyclin, PGF2 and PGE in the heart and blood plasma. The authors hold that the changes in the level of prostanoids may mediate cardioprotective and anti-stressor rather than antiarrhythmic effects of enkephalins.
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pubmed:language |
rus
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|
pubmed:journal |
|
|
pubmed:citationSubset |
IM
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pubmed:chemical |
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|
pubmed:status |
MEDLINE
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pubmed:issn |
0869-6047
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pubmed:author |
|
|
pubmed:issnType |
Print
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
47-51
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pubmed:dateRevised |
2008-11-21
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pubmed:meshHeading |
pubmed-meshheading:1284224-Animals,
pubmed-meshheading:1284224-Anti-Arrhythmia Agents,
pubmed-meshheading:1284224-Disease Models, Animal,
pubmed-meshheading:1284224-Drug Evaluation, Preclinical,
pubmed-meshheading:1284224-Enkephalin, Leucine-2-Alanine,
pubmed-meshheading:1284224-Enkephalin, Methionine,
pubmed-meshheading:1284224-Heart,
pubmed-meshheading:1284224-Myocardial Ischemia,
pubmed-meshheading:1284224-Myocardium,
pubmed-meshheading:1284224-Prostaglandins,
pubmed-meshheading:1284224-Stress, Physiological,
pubmed-meshheading:1284224-Ventricular Fibrillation
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pubmed:year |
1992
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pubmed:articleTitle |
[The participation of prostanoids in the realization of the cardioprotective, antistressor and anti-arrhythmic effects of enkephalins].
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pubmed:publicationType |
Journal Article,
Comparative Study,
English Abstract
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