Linked Life Data

12836215

Source:http://linkedlifedata.com/resource/pubmed/id/12836215

Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
4
pubmed:dateCreated
2003-7-2
pubmed:abstractText
The interface between two cells from the immune system has recently been coined "immunological synapse". The authors review recent findings concerning the structure of the synapse formed between T lymphocytes and antigen-presenting cells. T cells can be part of different synapses, depending on the antigen-presenting cell (B cell hybridoma, proteo-lipid bilayer, macrophage, dendritic cell). The synapse formed with dendritic cells is discussed in more details. A comparison is made with the synapses from the nervous system. Several parallel questions are discussed: how receptors can be clustered, what is the influence of synapse functioning on the structure of the synapse. It is suggested that in both cases two modes of communication exist in parallel: direct cell-cell contacts and soluble mediators, neurotransmitters in one case, putative immunotransmitters in the other.
pubmed:language
fre
pubmed:journal
pubmed:citationSubset
IM
pubmed:chemical
pubmed:status
MEDLINE
pubmed:month
Apr
pubmed:issn
0767-0974
pubmed:author
pubmed:issnType
Print
pubmed:volume
19
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
429-36
pubmed:dateRevised
2007-4-13
pubmed:meshHeading
pubmed:year
2003
pubmed:articleTitle
[Immunological synapses and neuronal synapses].
pubmed:affiliation
Département de Biologie Cellulaire, Institut Cochin, Inserm U.567, Cnrs UMR 8104, 22, rue Méchain, 75014 Paris, France. trautmann@cochin.inserm.fr
pubmed:publicationType
Journal Article, English Abstract, Review, Research Support, Non-U.S. Gov't