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pubmed-article:12833450pubmed:abstractTextAmplification of DNA in certain chromosomal regions plays a crucial role in the development and progression of human malignancies, specifically when protooncogenic target genes within those amplicons are overexpressed. Comparative genomic hybridization studies have revealed frequent amplification at 20q in primary breast tumors. The aim of the current study was to identify specific genes in the 20q amplicon that were likely to have clinical significance.lld:pubmed
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pubmed-article:12833450pubmed:copyrightInfoCopyright 2003 American Cancer Society.DOI 10.1002/cncr.11482lld:pubmed
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pubmed-article:12833450pubmed:articleTitleElevated expression levels of NCOA3, TOP1, and TFAP2C in breast tumors as predictors of poor prognosis.lld:pubmed
pubmed-article:12833450pubmed:affiliationDepartment of Molecular Cytogenetics, Medical Research Institute, Tokyo Medical and Dental University, Tokyo, Japan.lld:pubmed
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