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rdf:type |
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lifeskim:mentions |
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pubmed:dateCreated |
1993-2-22
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pubmed:abstractText |
EBV infections were studied in paraffin embedded lymph node specimens (n = 20) on DNA, protein, and histological level. The lymph nodes were obtained from 20 patients all testing positive for EBV serologically. The EBV DNA was detected by non radioactive in-situ-hybridisation using the BamHI W fragment of the virus. The EBV latent membrane protein was detected immunohistochemically using the LMP antibody (DAKO). Infected cells were characterized by monoclonal B cell antibodies. By in-situ-hybridization we found positive signals for EBV in all specimens. In contrast, no LMP was detectable immunohistochemically in 2/20 lymph nodes.
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pubmed:language |
ger
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pubmed:journal |
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pubmed:citationSubset |
IM
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pubmed:chemical |
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pubmed:status |
MEDLINE
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pubmed:issn |
0070-4113
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pubmed:author |
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pubmed:issnType |
Print
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pubmed:volume |
76
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
211-2
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pubmed:dateRevised |
2006-11-15
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pubmed:meshHeading |
pubmed-meshheading:1283261-Antibodies, Monoclonal,
pubmed-meshheading:1283261-Antigens, Viral,
pubmed-meshheading:1283261-DNA, Viral,
pubmed-meshheading:1283261-DNA-Binding Proteins,
pubmed-meshheading:1283261-Epstein-Barr Virus Nuclear Antigens,
pubmed-meshheading:1283261-Herpesvirus 4, Human,
pubmed-meshheading:1283261-Humans,
pubmed-meshheading:1283261-Immunohistochemistry,
pubmed-meshheading:1283261-In Situ Hybridization,
pubmed-meshheading:1283261-Lymph Nodes,
pubmed-meshheading:1283261-Lymphadenitis,
pubmed-meshheading:1283261-Restriction Mapping
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pubmed:year |
1992
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pubmed:articleTitle |
[EBV-lymphadenitis: diagnostic possibilities using immunohistochemistry and in situ hybridization].
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pubmed:affiliation |
Institut für Allgemeine Pathologie und Pathologische Anatomie, Christian-Albrechts-Universität, Kiel.
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pubmed:publicationType |
Journal Article,
English Abstract
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