Source:http://linkedlifedata.com/resource/pubmed/id/12830402
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rdf:type | |
lifeskim:mentions | |
pubmed:issue |
1
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pubmed:dateCreated |
2003-6-27
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pubmed:abstractText |
During summer and fall, enterovirus infections are responsible for a considerable proportion of hospitalizations of young infants. We prospectively studied the incidence of enterovirus infections via real-time polymerase chain reaction (PCR) in blood, feces, and cerebrospinal fluid samples from infants <or=60 days old who had received a clinical diagnosis of sepsis. Forty-five patients were included: 19 were admitted to the pediatric wards of 2 general hospitals, and 26 had been hospitalized since birth in the neonatal intensive care unit (NICU) of a tertiary care hospital. None of the NICU patients developed enteroviral disease. In contrast, an enterovirus was detected in 11 (58%) of the patients admitted to the 2 general hospitals, 10 of whom (53%) showed evidence of systemic infection. Enterovirus infections are an important cause of sepsis in infants admitted to the hospital. Real-time PCR in serum was a rapid and sensitive method for diagnosis of enterovirus infection.
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pubmed:language |
eng
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pubmed:journal | |
pubmed:citationSubset |
IM
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pubmed:status |
MEDLINE
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pubmed:month |
Jul
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pubmed:issn |
1537-6591
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pubmed:author |
pubmed-author:DieperslootR J ARJ,
pubmed-author:FleetCC,
pubmed-author:GerardsL JLJ,
pubmed-author:KredietT GTG,
pubmed-author:NijhuisMM,
pubmed-author:Pekelharing-BerghuisM AMA,
pubmed-author:ThijsenS F TSF,
pubmed-author:Verboon-MaciolekM AMA,
pubmed-author:van LoonA MAM,
pubmed-author:van MaarssenveenNN,
pubmed-author:van WieringenHH
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pubmed:issnType |
Electronic
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pubmed:day |
1
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pubmed:volume |
37
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
1-6
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pubmed:dateRevised |
2004-11-17
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pubmed:meshHeading |
pubmed-meshheading:12830402-Enterovirus,
pubmed-meshheading:12830402-Enterovirus Infections,
pubmed-meshheading:12830402-Female,
pubmed-meshheading:12830402-Humans,
pubmed-meshheading:12830402-Infant,
pubmed-meshheading:12830402-Male,
pubmed-meshheading:12830402-Polymerase Chain Reaction,
pubmed-meshheading:12830402-Sensitivity and Specificity
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pubmed:year |
2003
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pubmed:articleTitle |
Diagnosis of enterovirus infection in the first 2 months of life by real-time polymerase chain reaction.
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pubmed:affiliation |
Department of Neonatology, Eijkman Winkler Institute for Microbiology, Infectious Diseases, and Inflammation, University Medical Center, Utrecht, The Netherlands. M.Verboon-Maciolek@wkz.azu.nl
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pubmed:publicationType |
Journal Article
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