Source:http://linkedlifedata.com/resource/pubmed/id/12824869
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Predicate | Object |
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rdf:type | |
lifeskim:mentions | |
pubmed:issue |
1
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pubmed:dateCreated |
2003-6-25
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pubmed:abstractText |
Ghrelin is an acylated peptide, whose octanoyl modification is essential for its biological activities. Previous studies demonstrated that fasting plasma ghrelin levels were high in anorectic patients, suggesting ghrelin may play an important role in the pathophysiology of anorexia nervosa. However, antibodies used in previous work to measure ghrelin concentrations in human blood do not distinguish between the active form of ghrelin (active ghrelin) and desacyl ghrelin with no biological activities. Therefore, we studied plasma levels of active ghrelin during oral glucose tolerance test (OGTT) in anorectic patients, using a radioimmunoassay (RIA) specific for active ghrelin.
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pubmed:language |
eng
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pubmed:journal | |
pubmed:citationSubset |
IM
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pubmed:chemical | |
pubmed:status |
MEDLINE
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pubmed:month |
Jul
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pubmed:issn |
0804-4643
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pubmed:author | |
pubmed:issnType |
Print
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pubmed:volume |
149
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
R1-3
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pubmed:dateRevised |
2007-11-15
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pubmed:meshHeading |
pubmed-meshheading:12824869-Anorexia Nervosa,
pubmed-meshheading:12824869-Female,
pubmed-meshheading:12824869-Ghrelin,
pubmed-meshheading:12824869-Glucose,
pubmed-meshheading:12824869-Glucose Tolerance Test,
pubmed-meshheading:12824869-Humans,
pubmed-meshheading:12824869-Peptide Hormones,
pubmed-meshheading:12824869-Radioimmunoassay
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pubmed:year |
2003
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pubmed:articleTitle |
Plasma levels of active form of ghrelin during oral glucose tolerance test in patients with anorexia nervosa.
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pubmed:affiliation |
College of Medical Technology, Kyoto University, Kyoto University Hospital, 53 Kawaharacho, Shogoin, Sakyo-ku, Kyoto, 606-8507, Japan. YN@itan.kyoto-u.ac.jp
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pubmed:publicationType |
Journal Article,
Research Support, Non-U.S. Gov't
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