Linked Life Data

12824731

Source:http://linkedlifedata.com/resource/pubmed/id/12824731

Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
2
pubmed:dateCreated
2003-6-25
pubmed:abstractText
Mix-mice, a new strain of mice with inner ear dysfunction, and their littermates were used in the present study in order to investigate vestibular morphology, visualised by light microscopy (LM) and transmission electron microscopy (TEM). Contrary to the mix-mice, their littermates showed less stained nerve chalices and it was possible to detect that hair cells showed surface herniations and so-called 'blebs' in the apical portion of the epithelium. Sensory hairs showed a disarrayed pattern. The mix-mice had severe microscopical abnormalities: collapse of the membranous cell layer, cavities inside the neuroepithelium, severe loss of hair cells, herniations of the few remaining hair cells and increased supporting cells were evident. In the utricle and saccule, hair cells were missing and the epithelial surface was covered by a single layer of smooth, flattened epithelial cells of hitherto unknown origin.
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:status
MEDLINE
pubmed:issn
0301-1569
pubmed:author
pubmed:copyrightInfo
Copyright 2003 S. Karger AG, Basel
pubmed:issnType
Print
pubmed:volume
65
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
97-102
pubmed:dateRevised
2007-11-15
pubmed:meshHeading
pubmed:articleTitle
Vestibular morphology in the mutant mix-mouse.
pubmed:affiliation
Institute for Hearing and Communication Research, Karolinska Institutet, Karolinska Hospital, Stockholm, Sweden. haruent@hotmail.com
pubmed:publicationType
Journal Article, Comparative Study