Linked Life Data

12824688

Source:http://linkedlifedata.com/resource/pubmed/id/12824688

Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
2
pubmed:dateCreated
2003-6-25
pubmed:abstractText
Chlamydia pneumoniae is a common pathogen that causes upper and lower respiratory tract infections and is difficult to isolate from clinical specimens. Recently, we succeeded in isolating the first C. pneumoniae strain in Korea. This study characterizes the morphology, infectivity, and drug sensitivity of the Korean strain, designated LKK-1. Electron microscopy was performed for thin sections, and the infectivity over time was tested by counting the inclusion-forming units every 12 h. The minimum inhibitory concentrations of doxycycline, erythromycin, clarithromycin, ciprofloxacin, and levofloxacin were determined following the standard Japanese method. The elementary bodies of LKK-1 were round, like those in Japanese strain KKpn-1, whereas those of TW-183 have wavy cell membranes and are pear-shaped. The infectivity curve and drug sensitivities of LKK-1 were nearly the same as those of KKpn-1. In conclusion, LKK-1, the first strain from Korea, is similar to the Japanese strain KKpn-1 in terms of morphology, growth, and drug sensitivities, and shows a distinct difference in morphology compared with TW-183. Further studies are needed to elucidate the morphological differences between round strains and classical pear-shaped strains of C. pneumoniae.
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:chemical
pubmed:status
MEDLINE
pubmed:month
Apr
pubmed:issn
1344-6304
pubmed:author
pubmed:issnType
Print
pubmed:volume
56
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
62-4
pubmed:dateRevised
2006-11-15
pubmed:meshHeading
pubmed:year
2003
pubmed:articleTitle
Characterization of the first Korean isolate of a Chlamydia pneumoniae strain.
pubmed:affiliation
Department of Internal Medicine, Kangwon National University, Kangwon 200-701, Korea. medfman@knuh.or.kr
pubmed:publicationType
Journal Article, Research Support, Non-U.S. Gov't