rdf:type |
|
lifeskim:mentions |
|
pubmed:issue |
7
|
pubmed:dateCreated |
2003-6-25
|
pubmed:abstractText |
Protective effects of estrogen on nerve cells including retinal neurons have been described previously. However, subcellular effects on synaptic connectivity in mild ischemia more closely resembling ischemic conditions found in diabetic or sickle cell retinopathy and stenosis of the carotid artery have not been identified. The present study quantitatively analyzed effects of estrogen administration on synaptic connections of neurons in the ganglion cell layer (GCL) of the retina.
|
pubmed:language |
eng
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pubmed:journal |
|
pubmed:citationSubset |
IM
|
pubmed:chemical |
|
pubmed:status |
MEDLINE
|
pubmed:month |
Jul
|
pubmed:issn |
0146-0404
|
pubmed:author |
|
pubmed:issnType |
Print
|
pubmed:volume |
44
|
pubmed:owner |
NLM
|
pubmed:authorsComplete |
Y
|
pubmed:pagination |
3155-62
|
pubmed:dateRevised |
2006-11-15
|
pubmed:meshHeading |
pubmed-meshheading:12824266-Animals,
pubmed-meshheading:12824266-Apoptosis,
pubmed-meshheading:12824266-Biological Markers,
pubmed-meshheading:12824266-Carrier Proteins,
pubmed-meshheading:12824266-Estrogens,
pubmed-meshheading:12824266-Female,
pubmed-meshheading:12824266-Fluorescent Antibody Technique, Indirect,
pubmed-meshheading:12824266-In Situ Nick-End Labeling,
pubmed-meshheading:12824266-Ischemia,
pubmed-meshheading:12824266-Microscopy, Immunoelectron,
pubmed-meshheading:12824266-Neurons,
pubmed-meshheading:12824266-Neuropeptides,
pubmed-meshheading:12824266-Neuroprotective Agents,
pubmed-meshheading:12824266-Rats,
pubmed-meshheading:12824266-Rats, Sprague-Dawley,
pubmed-meshheading:12824266-Retinal Diseases,
pubmed-meshheading:12824266-Retinal Ganglion Cells,
pubmed-meshheading:12824266-Retinal Vessels,
pubmed-meshheading:12824266-Synapses
|
pubmed:year |
2003
|
pubmed:articleTitle |
Estrogen protects the inner retina from apoptosis and ischemia-induced loss of Vesl-1L/Homer 1c immunoreactive synaptic connections.
|
pubmed:affiliation |
University of North Texas Health Science Center at Fort Worth, Department of Pharmacology and Neuroscience, Fort Worth, Texas 76107-2699, USA.
|
pubmed:publicationType |
Journal Article,
Research Support, Non-U.S. Gov't
|