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12824013
Source:
http://linkedlifedata.com/resource/pubmed/id/12824013
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Statements in which the resource exists as a subject.
Predicate
Object
rdf:type
pubmed:Citation
lifeskim:mentions
umls-concept:C0220781
,
umls-concept:C0449432
,
umls-concept:C0679199
,
umls-concept:C1179435
,
umls-concept:C1524073
,
umls-concept:C1548799
,
umls-concept:C1705248
,
umls-concept:C1883254
,
umls-concept:C1948027
,
umls-concept:C2267054
pubmed:issue
14
pubmed:dateCreated
2003-6-25
pubmed:abstractText
A novel isonitrile derivative was synthesized and used in an Ugi four component coupling reaction to explore aryl group substitution effects on inhibition of the coagulation cascade serine protease factor Xa.
pubmed:language
eng
pubmed:journal
http://linkedlifedata.com/resource/pubmed/journal/9107377
pubmed:citationSubset
IM
pubmed:chemical
http://linkedlifedata.com/resource/pubmed/chemical/Factor Xa
,
http://linkedlifedata.com/resource/pubmed/chemical/Glycine
,
http://linkedlifedata.com/resource/pubmed/chemical/Indicators and Reagents
,
http://linkedlifedata.com/resource/pubmed/chemical/Serine Proteinase Inhibitors
,
http://linkedlifedata.com/resource/pubmed/chemical/phenylglycinamide
pubmed:status
MEDLINE
pubmed:month
Jul
pubmed:issn
0960-894X
pubmed:author
pubmed-author:EngelDavid BDB
,
pubmed-author:FarmenMark WMW
,
pubmed-author:FranciskovichJeffrey BJB
,
pubmed-author:JonesStuart DSD
,
pubmed-author:KyleJeffrey AJA
,
pubmed-author:LiebeschuetzJohn WJW
,
pubmed-author:MarimuthuJothirajahJ
,
pubmed-author:MastersJohn JJJ
,
pubmed-author:MurrayChristopher WCW
,
pubmed-author:SheehanScott MSM
,
pubmed-author:SmallwoodJeffrey KJK
,
pubmed-author:SmithGerald FGF
,
pubmed-author:WeberWayne WWW
,
pubmed-author:WileyMichael RMR
,
pubmed-author:YoungStephen CSC
pubmed:issnType
Print
pubmed:day
21
pubmed:volume
13
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
2255-9
pubmed:meshHeading
pubmed-meshheading:12824013-Factor Xa
,
pubmed-meshheading:12824013-Glycine
,
pubmed-meshheading:12824013-Indicators and Reagents
,
pubmed-meshheading:12824013-Serine Proteinase Inhibitors
,
pubmed-meshheading:12824013-Structure-Activity Relationship
pubmed:year
2003
pubmed:articleTitle
A four component coupling strategy for the synthesis of D-phenylglycinamide-derived non-covalent factor Xa inhibitors.
pubmed:affiliation
Lilly Research Laboratories, A Division of Eli Lilly and Company, IN 46285, Indianapolis, USA. sheehan_scott@lilly.com
pubmed:publicationType
Journal Article