Linked Life Data

12821790

Source:http://linkedlifedata.com/resource/pubmed/id/12821790

Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
8
pubmed:dateCreated
2003-6-24
pubmed:abstractText
Is functional neuroimaging a royal way to understand brain function or is it a new phrenology without an exact understanding what we measure? After two decades of imaging revolution, more and more authors ask this question. Brain functions are multidimensional, which can be approached from the point of (1) behavioural measures, (2) brain activation as reflected by blood flow and metabolic changes, (3) electrical activity of cells and cell-populations, and (4) neurotransmitter dynamics (release, receptor binding and reuptake). Using imaging techniques, we must take into consideration that even during the simplest task all of these processes operate in a closely interacting manner. Therefore, before drawing final conclusions about brain functions on the basis of a single aspect of these mechanisms, we must clarify the exact relationship among them. In this paper, we address this issue in order to draw attention to a number of uncertainties and controversies in the relationship of the four facets of brain functions.
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:chemical
pubmed:status
MEDLINE
pubmed:month
Jun
pubmed:issn
0959-4965
pubmed:author
pubmed:issnType
Print
pubmed:day
11
pubmed:volume
14
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
1097-106
pubmed:dateRevised
2006-11-15
pubmed:meshHeading
pubmed:year
2003
pubmed:articleTitle
Four facets of a single brain: behaviour, cerebral blood flow/metabolism, neuronal activity and neurotransmitter dynamics.
pubmed:affiliation
Department of Clinical Neuroscience, Psychiatry Section, Karolinska Institute, Stockholm, Sweden.
pubmed:publicationType
Journal Article, Review, Research Support, Non-U.S. Gov't