Source:http://linkedlifedata.com/resource/pubmed/id/12821355
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Predicate | Object |
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rdf:type | |
lifeskim:mentions | |
pubmed:issue |
1
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pubmed:dateCreated |
2003-6-24
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pubmed:abstractText |
The 3' untranslated region of the prohibitin gene encodes an RNA molecule that arrests cell proliferation between the G(1) and S phases of the cell cycle, and a C-to-T transition within this region creates a variant lacking antiproliferative activity. The T allele was reported to be associated with an increased risk of breast cancer in North American women, specifically in those under age 50 years reporting a first-degree family history of breast cancer. We assessed the association of the prohibitin 3' untranslated region polymorphism with risk of ovarian cancer in the Australian population by case-control comparison.
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pubmed:language |
eng
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pubmed:journal | |
pubmed:citationSubset |
IM
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pubmed:chemical | |
pubmed:status |
MEDLINE
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pubmed:month |
Jul
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pubmed:issn |
0090-8258
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pubmed:author | |
pubmed:issnType |
Print
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pubmed:volume |
90
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
145-9
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pubmed:dateRevised |
2006-11-15
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pubmed:meshHeading |
pubmed-meshheading:12821355-3' Untranslated Regions,
pubmed-meshheading:12821355-Adult,
pubmed-meshheading:12821355-Aged,
pubmed-meshheading:12821355-Case-Control Studies,
pubmed-meshheading:12821355-Female,
pubmed-meshheading:12821355-Genetic Predisposition to Disease,
pubmed-meshheading:12821355-Humans,
pubmed-meshheading:12821355-Middle Aged,
pubmed-meshheading:12821355-Ovarian Neoplasms,
pubmed-meshheading:12821355-Polymorphism, Genetic,
pubmed-meshheading:12821355-Proteins,
pubmed-meshheading:12821355-Repressor Proteins,
pubmed-meshheading:12821355-Risk Factors
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pubmed:year |
2003
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pubmed:articleTitle |
The prohibitin 3' untranslated region polymorphism is not associated with risk of ovarian cancer.
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pubmed:affiliation |
Cancer and Cell Biology Division, The Queensland Institute of Medical Research, Herston, PO Royal Brisbane Hospital, Queensland 4029, Australia. mandyS@qimr.edu.au
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pubmed:publicationType |
Journal Article,
Research Support, Non-U.S. Gov't
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