Linked Life Data

12821281

Source:http://linkedlifedata.com/resource/pubmed/id/12821281

Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
1-2
pubmed:dateCreated
2003-6-24
pubmed:abstractText
Cells continuously produce free radicals and reactive oxygen species (ROS) as part of metabolic processes. These free radicals are neutralized by an elaborate antioxidant defense system consisting of enzymes such as catalase, superoxide dismutase, glutathione peroxidase, and numerous non-enzymatic antioxidants, including vitamins A, E and C, glutathione, ubiquinone, and flavonoids. Exercise can produce an imbalance between ROS and antioxidants, which is referred to as oxidative stress. Dietary antioxidant supplements are marketed to and used by athletes as a means to counteract the oxidative stress of exercise. Whether strenuous exercise does, in fact, increase the need for additional antioxidants in the diet is not clear. This review examines the markers used to determine oxidative stress in blood and muscle samples (e.g. lipid peroxidation, expired pentane, malondialdehyde (MDA), F2-isoprostanes, congugated dienes, and 8-hydroxy-2'-deoxyguanosine (8-OhdG)), the changes in oxidative stress markers induced by exercise, and whether athletes require antioxidant supplements.
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:chemical
pubmed:status
MEDLINE
pubmed:month
Jul
pubmed:issn
0300-483X
pubmed:author
pubmed:issnType
Print
pubmed:day
15
pubmed:volume
189
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
41-54
pubmed:dateRevised
2005-11-16
pubmed:meshHeading
pubmed:year
2003
pubmed:articleTitle
Oxidative stress, exercise, and antioxidant supplementation.
pubmed:affiliation
Exercise Science Department, University of Massachusetts, 110 Totman Building, Amherst, MA 01003, USA. murso@exsci.umass.edu
pubmed:publicationType
Journal Article, Review