Linked Life Data

12815721

Source:http://linkedlifedata.com/resource/pubmed/id/12815721

Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
7
pubmed:dateCreated
2003-6-19
pubmed:abstractText
The virulence of a virus is determined by its ability to adversely affect the host cell, host organism or population of host organisms. Influenza A viruses have been responsible for four pandemics of severe human respiratory disease this century. Avian species harbour a large reservoir of influenza virus strains, which can contribute genes to potential new pandemic human strains. The fundamental importance of understanding the role of each of these genes in determining virulence in birds and humans was dramatically emphasised by the recent direct transmission of avian influenza A viruses to humans, causing fatal infection but not community spread. An understanding of the factors involved in transmission between avian and mammalian species should assist in the development of better surveillance strategies for early recognition of influenza A virus strains having human pandemic potential, and possibly in the design of anti-viral strategies.
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:status
MEDLINE
pubmed:month
Jul
pubmed:issn
0265-9247
pubmed:author
pubmed:copyrightInfo
Copyright 2003 Wiley Periodicals, Inc.
pubmed:issnType
Print
pubmed:volume
25
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
657-71
pubmed:dateRevised
2005-11-22
pubmed:meshHeading
pubmed:year
2003
pubmed:articleTitle
Influenza type A in humans, mammals and birds: determinants of virus virulence, host-range and interspecies transmission.
pubmed:affiliation
Division of Molecular Biology, Institute for Animal Health, Newbury, UK. sue.baigent@bbsrc.ac.uk
pubmed:publicationType
Journal Article, Review