Source:http://linkedlifedata.com/resource/pubmed/id/12815696
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Predicate | Object |
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rdf:type | |
lifeskim:mentions | |
pubmed:issue |
1
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pubmed:dateCreated |
2003-6-19
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pubmed:abstractText |
Stem cell transplantation is being explored as a new paradigm for the treatment of demyelinating diseases. Magnetically labeled multipotential neural precursor cells were transplanted into the ventricles of rats with acute experimental allergic encephalomyelitis (EAE) and high-resolution (microscopic) MR images were obtained ex vivo. Migration patterns of live cells into periventricular white matter structures could be easily visualized, with a good correlation of the corresponding histopathology. The present results confirm that MR cell tracking can be used to guide the development of successful transplantation protocols.
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pubmed:grant | |
pubmed:language |
eng
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pubmed:journal | |
pubmed:citationSubset |
IM
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pubmed:chemical | |
pubmed:status |
MEDLINE
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pubmed:month |
Jul
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pubmed:issn |
0740-3194
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pubmed:author | |
pubmed:copyrightInfo |
Copyright 2003 Wiley-Liss, Inc.
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pubmed:issnType |
Print
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pubmed:volume |
50
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
201-5
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pubmed:dateRevised |
2011-11-17
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pubmed:meshHeading |
pubmed-meshheading:12815696-Animals,
pubmed-meshheading:12815696-Brain,
pubmed-meshheading:12815696-Cell Movement,
pubmed-meshheading:12815696-Contrast Media,
pubmed-meshheading:12815696-Encephalomyelitis, Autoimmune, Experimental,
pubmed-meshheading:12815696-Female,
pubmed-meshheading:12815696-Ferumoxytol,
pubmed-meshheading:12815696-Iron,
pubmed-meshheading:12815696-Magnetic Resonance Spectroscopy,
pubmed-meshheading:12815696-Microscopy,
pubmed-meshheading:12815696-Microspheres,
pubmed-meshheading:12815696-Neurons,
pubmed-meshheading:12815696-Oxides,
pubmed-meshheading:12815696-Rats,
pubmed-meshheading:12815696-Rats, Inbred Lew,
pubmed-meshheading:12815696-Staining and Labeling,
pubmed-meshheading:12815696-Stem Cell Transplantation,
pubmed-meshheading:12815696-Stem Cells
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pubmed:year |
2003
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pubmed:articleTitle |
MR microscopy of magnetically labeled neurospheres transplanted into the Lewis EAE rat brain.
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pubmed:affiliation |
Department of Radiology and Radiological Sciences, Johns Hopkins University School of Medicine, Baltimore, Maryland 21205-2195, USA. jwmbulte@mri.jhu.edu
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pubmed:publicationType |
Journal Article,
Comparative Study,
Research Support, U.S. Gov't, P.H.S.,
Research Support, Non-U.S. Gov't,
Evaluation Studies,
Validation Studies
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