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rdf:type |
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lifeskim:mentions |
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pubmed:dateCreated |
2003-6-18
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pubmed:abstractText |
The purpose of the study was to evaluate the possible occurrence of loss of heterozygosity (LOH) in the anterior capsule, lens nucleus, iris, and trabeculum samples taken from patients with pseudoexfoliation syndrome (PEX). Loss of heterozygosity in a microsatellite marker locus indicates that the neighboring gene may be inactivated. Previous attempts to find a gene defect that might be responsible for pseudoexfoliation glaucoma have been unsuccessful.
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pubmed:language |
eng
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pubmed:journal |
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pubmed:citationSubset |
IM
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pubmed:chemical |
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pubmed:status |
MEDLINE
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pubmed:month |
Jun
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pubmed:issn |
1090-0535
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pubmed:author |
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pubmed:issnType |
Electronic
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pubmed:day |
17
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pubmed:volume |
9
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
257-61
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pubmed:dateRevised |
2006-11-15
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pubmed:meshHeading |
pubmed-meshheading:12813407-Aged,
pubmed-meshheading:12813407-Aged, 80 and over,
pubmed-meshheading:12813407-Cataract Extraction,
pubmed-meshheading:12813407-Chromosomes, Human,
pubmed-meshheading:12813407-DNA,
pubmed-meshheading:12813407-Exfoliation Syndrome,
pubmed-meshheading:12813407-Female,
pubmed-meshheading:12813407-Gene Deletion,
pubmed-meshheading:12813407-Glaucoma,
pubmed-meshheading:12813407-Humans,
pubmed-meshheading:12813407-Iris,
pubmed-meshheading:12813407-Lens Capsule, Crystalline,
pubmed-meshheading:12813407-Lens Nucleus, Crystalline,
pubmed-meshheading:12813407-Loss of Heterozygosity,
pubmed-meshheading:12813407-Male,
pubmed-meshheading:12813407-Microsatellite Repeats,
pubmed-meshheading:12813407-Middle Aged,
pubmed-meshheading:12813407-Polymerase Chain Reaction,
pubmed-meshheading:12813407-Trabecular Meshwork,
pubmed-meshheading:12813407-Trabeculectomy
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pubmed:year |
2003
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pubmed:articleTitle |
Loss of heterozygosity in patients with pseudoexfoliation syndrome.
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pubmed:affiliation |
Department of Ophthalmology, Medical University of Bialystok, Bialystok, Poland.
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pubmed:publicationType |
Journal Article,
Research Support, Non-U.S. Gov't
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